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Access to large cyclic peptides by a one-pot two-peptide segment ligation/cyclization process. | LitMetric

AI Article Synopsis

Article Abstract

The use of the N-acetoacetyl protecting group for N-terminal cysteine residue enabled creation of an efficient and mild one-pot native chemical ligation/SEA ligation sequence giving access to large cyclic peptides.

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Source
http://dx.doi.org/10.1021/ol503359wDOI Listing

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