Trends in antimicrobial resistance in Neisseria gonorrhoeae isolated from Guangzhou, China, 2000 to 2005 and 2008 to 2013.

Sex Transm Dis

From the *Institute of Dermatology, Guangzhou Medical University, Guangzhou, PR China; and †Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, PR China.

Published: January 2015

AI Article Synopsis

  • - A study examined 1224 Neisseria gonorrhoeae isolates from Guangzhou over two periods (2000-2005 and 2008-2013) for antimicrobial susceptibility.
  • - Resistance to penicillin increased from 71.1% to 90.9%, and resistance to ciprofloxacin rose from 88.9% to 98.0% during the study.
  • - Despite rising minimum inhibitory concentrations, all isolates were still susceptible to spectinomycin and ceftriaxone.

Article Abstract

A total of 1224 Neisseria gonorrhoeae isolates from Guangzhou in 2 periods (2000-2005 and 2008-2013) were subjected to antimicrobial susceptibility testing. The percentage of penicillin- and ciprofloxacin-resistant isolates increased from 71.1% (473/665) to 90.9% (508/559) and 88.9% (591/665) to 98.0% (548/559), respectively. All isolates remain susceptible to spectinomycin and ceftriaxone, with increasing minimum inhibitory concentrations.

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Source
http://dx.doi.org/10.1097/OLQ.0000000000000218DOI Listing

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