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Changes in seasonal influenza vaccination uptake among older adults during and after the COVID-19 pandemic: Repeated random telephone surveys.
Hum Vaccin Immunother
December 2025
Centre for Health Behavious Research, Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China.
People's risk of contracting seasonal influenza increased after COVID-19 control measures were relaxed. This study investigated the changes in seasonal influenza vaccination (SIV) uptake and its determinants among older adults during and after the COVID-19 period. Two rounds of random telephone surveys were conducted among 440 and 373 community-living individuals aged ≥65 y, the first between November 2021 and January 2022 and the second between October 2023 and January 2024.
View Article and Find Full Text PDFHigh-resolution melting analysis for detection of nucleotide mutation markers in the polymerase-acidic (PA) gene of influenza virus that are associated with baloxavir marboxil resistance.
Arch Virol
January 2025
Department Experimental and Clinical Medicine, University of Florence, Florence, Italy.
The I38T substitution in the influenza virus polymerase-acidic (PA) subunit is a resistance marker of concern for treatment with the antiviral baloxavir marboxil (BXM). Thus, monitoring PA/I38T mutations is of clinical importance. Here, we developed three rapid and sensitive assays for the detection and monitoring of the PA/I38T mutation.
View Article and Find Full Text PDFNext-generation vaccines for influenza B virus: advancements and challenges.
Arch Virol
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CAS Key Laboratory of Molecular Virology & Immunology, Institutional Center for Shared Technologies and Facilities, Pathogen Discovery and Big Data Platform, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Yueyang Road 320, Shanghai, 200031, China.
To battle seasonal outbreaks of influenza B virus infection, which continue to pose a major threat to world health, new and improved vaccines are urgently needed. In this article, we discuss the current state of next-generation influenza B vaccine development, including both advancements and challenges. This review covers the shortcomings of existing influenza vaccines and stresses the need for more-effective and broadly protective vaccines and more-easily scalable manufacturing processes.
View Article and Find Full Text PDFEpidemiology of respiratory viruses according to age group, 2023-24 winter season, Kyoto, Japan.
Sci Rep
January 2025
Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
The seasonality and epidemiology of viral acute respiratory infections (ARIs) have changed since the coronavirus disease 2019 pandemic. However, molecular-based ARI surveillance has not been conducted in Japan. We developed a regional surveillance program to define the local epidemiology of ARIs.
View Article and Find Full Text PDFInfluenza vaccine effectiveness against medically attended outpatient illness, United States, 2023-24 season.
Clin Infect Dis
January 2025
Influenza Division, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Background: The 2023-24 U.S. influenza season was characterized by a predominance of A(H1N1)pdm09 virus circulation with co-circulation of A(H3N2) and B/Victoria viruses.
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