Objectives: The study was conducted to evaluate our results of acute aortic dissection repair taking into account the impact of surgical experience in aortic surgery.
Methods: Between August 2002 and March 2013, 162 consecutive patients (mean age: 63 ± 14 years) underwent surgery for acute type A aortic dissection. All patients were operated on by one of the clinic's attending surgeons with wide experience in cardiac surgery (at least 2000 procedures performed personally), however about one-half of the patients (75 patients, 46%) were operated by the aortic team (AT) surgeons with profound experience in complex aortic pathologies. All perioperative data were collected prospectively and retrospective statistical analysis was performed using uni- and multivariate analyses to identify predictors for surgical adverse outcome (AO) containing in-hospital and/or 90-day mortality and new permanent neurological and organ dysfunctions.
Results: AO was observed in 36 patients (22.2%) including in-hospital mortality in 22 (13.6%). Multivariate logistic regression analysis identified surgery not performed by the AT as the strongest predictor for AO (odds ratio: 14.1; 95% confidence interval: 3.5-55.6; P < 0.0001) followed by any malperfusion, myocardial infarction and creatinine level. Two groups were built according to the surgery performed by the AT (Group AT) or by the surgeons not on the AT (Group No-AT). The comparison of the groups showed no relevant differences regarding the preoperative characteristics, especially compromised consciousness, malperfusion and extent of dissection. Yet, the outcomes in Group AT vs No-AT were significantly different presenting AO: 8.0 vs 34.5% (P < 0.0001), in-hospital mortality: 4.0 vs and 21.8% (P < 0.001), new permanent neurological deficit: 2.7 vs 11.5% (P = 0.03), even if valve-sparing repairs and complete arch replacements were much more frequent in Group AT. The groups also differed considerably in regard to cannulation and perfusion management, which might play a decisive role in surgical outcome.
Conclusions: Aortic repair in acute type A dissection, when performed by highly specialized aortic surgeons, offers not only much better outcomes but also provides significantly higher rate of curative albeit valve-sparing aortic repairs. Patient-centred care in referral aortic centres with surgery performed by specialized teams should be striven for to improve surgical results in acute aortic dissection surgery.
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http://dx.doi.org/10.1093/ejcts/ezu454 | DOI Listing |
Cureus
November 2024
Cardiovascular Surgery, Sapporo Medical University, Sapporo, JPN.
The patient an 85-year-old female resided in a care facility where she maintained an independent daily activity level. She was discovered hunched over a table in her room, displaying reduced responsiveness and prompting an emergency call. Initially, her blood pressure was within 60 mmHg, and she was transported by ambulance to our hospital.
View Article and Find Full Text PDFCureus
November 2024
Division of Cardiovascular Surgery, Department of Surgery, Kurume University, Kurume, JPN.
The outcomes of cardiac surgery in patients with hematologic disorders are significantly worse. However, details of the clinical course of each hematologic disease remain unclear. Myelodysplastic syndrome (MDS) presents with progressive pancytopenia that has the risk of infection, hemorrhage, and transformation to acute myelogenous leukemia.
View Article and Find Full Text PDFCureus
November 2024
Vascular Surgery, University of Colorado Anschutz Medical Center, Colorado, USA.
Fluoroquinolones (FQs) are a widely prescribed class of antibiotics including ciprofloxacin, levofloxacin, and ofloxacin. They are commonly used to treat a variety of infections worldwide. Known for their broad-spectrum antimicrobial activity, as well as excellent pharmacokinetics and bioavailability, the use of FQs has risen significantly.
View Article and Find Full Text PDFIn surgery for acute type A aortic dissection, controlling bleeding from the posterior wall of the proximal anastomosis is particularly challenging. To address this, we use the "reversed turn-up technique." For the reinforcement of the proximal aortic stump, Teflon felt strips were placed inside and outside the suture line with 4-0 polypropylene continuous transverse mattress sutures, and BioGlue was applied to the false lumen.
View Article and Find Full Text PDFJ Geriatr Cardiol
November 2024
Department of Cardiovascular Surgery, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Objective: To evaluate the benefits of surgical repair acute type A aortic dissection (ATAAD) on survival of octogenarians.
Methods: Patients who underwent surgery for acute ATAAD from the multicenter European Registry of Type A Aortic Dissection (ERTAAD) were the subjects of the present analysis.
Results: 326 (8.
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