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BA inhibits LPS-stimulated inflammatory response and apoptosis in human middle ear epithelial cells by regulating the Nf-Kb/Iκbα axis.
Open Life Sci
December 2024
Department of ENT, Yueqing People's Hospital, 338, Qingyuan Road, Chengnan Street, Yueqing City, Wenzhou, Zhejiang, 325600, China.
Otitis media (OM) is a prevalent childhood ear disease characterized by inflammation of the middle ear cavity, which can lead to ear pain, fever, and hearing loss. The pathogenesis of OM is multifaceted, encompassing a variety of factors including bacterial or viral infections, host immune responses, and the function of middle ear epithelial cells. Boswellic acid (BA), a natural triterpene compound extracted from frankincense resin, has been proven to possess significant anti-inflammatory and immunomodulatory effects.
View Article and Find Full Text PDFSmall Cell Neuroendocrine Carcinoma of the Nasopharynx.
J Craniofac Surg
November 2024
Department of Otolaryngology Head and Neck Surgery, Second Affiliated Hospital of Naval Medical University.
Background: Nasopharyngeal malignant tumors were relatively rare head and neck tumors with a low global incidence. There were various pathologic types of nasopharyngeal malignant tumors, and small cell neuroendocrine carcinoma (SCNEC) was a highly malignant subtype with rapid growth and early metastasis. SCNEC was rare in the nasopharynx, and its clinical presentation and treatment strategy were different from other types of nasopharyngeal malignancies, posing a challenge to clinicians.
View Article and Find Full Text PDFThe insane path of two cervical intervertebral implants: late migration, esophageal ingrowth, and rectal excretion: an exceptional case report.
J Spine Surg
December 2024
Spinal Surgery Team, Wirbelsäulenzentrum Ostschweiz AG, St. Gallen, Switzerland.
Background: The objective of this report is to present a case of two cervical spine artificial discs (Bryan Cervical Disk) that completely disappeared within 6 months as a result of a high-energy trauma more than 10 years after the initial surgery. Implant dislocation is a known complication in artificial cervical disc replacement. However, this report presents the case of an exceptional migration path with esophageal ingrowth and rectal excretion, not only for one artificial disc but for two at different times It highlights the need for long-term follow-up examinations after artificial cervical disc arthroplasty (ACDA).
View Article and Find Full Text PDFA Rare Case of Ramsey Hunt Syndrome With Cranial Polyneuropathy: Findings of the Brain MRI.
Cureus
December 2024
Department of Interventional Neuroradiology, University Hospital of Patras, Patras, GRC.
In this case, we present the case of a 74-year-old female patient who visited the University Hospital of Patras, Greece, because of a 10-day history of earache and discharge in the left ear. Concurrently, the patient exhibited ipsilateral peripheral facial nerve palsy. We also observed vesicular eruption at the auricle and the external auditory canal (EAC) of the left ear.
View Article and Find Full Text PDFAn Unusual Acute Otitis Media Complication: Luc's Abscess.
Turk Arch Otorhinolaryngol
January 2025
University of Health Sciences Türkiye Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, Clincic of Otorhinolaryngology and Head & Neck Surgery, İstanbul, Türkiye.
Otitis media, a common childhood disease, can lead to serious complications such as acute mastoiditis and, rarely, Luc's abscess, with life-threatening consequences. Luc's abscess, a rare but severe complication, can occur without acute mastoiditis. This case report details a case of Luc's abscess in a 14-year-old girl with acute otitis media, presenting with ear pain, facial swelling, and hearing loss.
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