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Lung cancer risk and its potential association with PM in Bagmati province, Nepal-A spatiotemporal study from 2012 to 2021.
Front Public Health
December 2024
State Key Laboratory of Remote Sensing Science, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China.
Background: Despite examining the role of an association between particulate matter and lung cancer in low-income countries, studies on the association between long-term exposure to particulate matter and lung cancer risk are still contradictory. This study investigates the spatiotemporal distribution patterns of lung cancer incidence and potential association with particulate matter (PM) in Bagmati province, Nepal.
Methods: We performed a spatiotemporal study to analyze the LC - PM association, using LC and annual mean PM concentration data from 2012 to 2021.
The effects of emotional distress on attentional bias toward cigarette warnings according to smokers' anxiety levels.
Front Psychol
December 2024
Department of Psychology, Chung-Ang University, Seoul, Republic of Korea.
Anxiety is related with the substance use, including cigarette smoking. Avoidance is one of the strategies smokers with anxiety adopt to manage negative affect, which can be contradictory to a strategy of cigarette warnings that is used to induce negative affect to change smoking behaviors. Therefore, this study examined whether smokers' anxiety levels decrease their attentional biases toward cigarette warnings, especially in response to emotional distress.
View Article and Find Full Text PDFHaploinsufficiency of PDE2A causes in mice increased exploratory behavior associated with upregulation of neural nitric oxide synthase in the striatum.
Neurobiol Dis
December 2024
Department of Systems Medicine, Tor Vergata University, 00133 Rome, Italy.
Phosphodiesterase 2 A (PDE2A) function is stimulated by cGMP to catabolize cAMP. However, neurological and neurochemical effects of PDE2A deficiency are poorly understood. To address this gap, we studied behavioral characteristics and cerebral morpho-chemical changes of adult male heterozygous C57BL/6-PDE2A+/- (HET), and wild type C57BL/6-PDE2A+/+ (WT) mice.
View Article and Find Full Text PDFAssociations of Serum Manganese, Zinc, Copper, and Selenium Concentrations With Autism Spectrum Disorders in Chinese Children: A Case-Control Study.
Autism Res
December 2024
School of Public Health, Hubei University of Medicine, Shiyan, China.
Imbalances in several trace elements related to antioxidant function may lead to autism spectrum disorder (ASD)-related physiological dysfunction. Nonetheless, contradictory results have been found on the connection between these elements and ASD, and studies of their joint effects and interactions have been insufficient. We therefore designed a case-control study of 152 ASD children and 152 age- and sex-matched typically developing (TD) children to explore the individual and combined associations of manganese (Mn), zinc (Zn), copper (Cu), and selenium (Se) with ASD.
View Article and Find Full Text PDFTetrodotoxin: The State-of-the-Art Progress in Characterization, Detection, Biosynthesis, and Transport Enrichment.
Mar Drugs
November 2024
Key Laboratory of Cultivation and High-Value Utilization of Marine Organisms in Fujian Province, Fisheries Research Institute of Fujian, National Research and Development Center for Marine Fish Processing, Xiamen 361021, China.
Tetrodotoxin (TTX) is a neurotoxin that binds to sodium channels and blocks sodium conduction. Importantly, TTX has been increasingly detected in edible aquatic organisms. Because of this and the lack of specific antidotes, TTX poisoning is now a major threat to public health.
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