Serum levels of brain-derived neurotrophic factor (BDNF) are reduced in male-to-female transsexual persons (MtF) compared to male controls. It was hypothesized before that this might reflect either an involvement of BDNF in a biomechanism of transsexualism or to be the result of persistent social stress due to the condition. Here, we demonstrate that 12 month of cross-sex hormone treatment reduces serum BDNF levels in male-to-female transsexual persons independent of anthropometric measures. Participants were acquired through the European Network for the Investigation of Gender Incongruence (ENIGI). Reduced serum BDNF in MtF thus seems to be a result of hormonal treatment rather than a consequence or risk factor of transsexualism.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.euroneuro.2014.11.019 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hide and Seek: Elmer Belt, Agnes, and the Battle over Castration in Transsexual Surgery, 1953-1962.
Bull Hist Med
November 2024
In the 1950s, the idea of sex change increasingly assumed the mainstay of public interest. As psychiatrists and psychologists developed new understandings of gender, the role of surgeons is often overlooked in the early history of sex reassignment. This article explores the work of one such doctor, Elmer Belt, a urologist based in Los Angeles.
View Article and Find Full Text PDFLaparoscopic sigmoid vaginoplasty for vaginal revision in a male-to-female transsexual-a video vignette.
Colorectal Dis
October 2024
Department of Colorectal Surgery, Changzheng Hospital, Navy Medical University, Shanghai, China.
Ulcerative colitis in a transgender woman with a sigmoid neovagina: a case report.
Int J Colorectal Dis
July 2024
Digestive Disease Research Institute (DDRI), Tehran University of Medical Sciences, Tehran, 14117-13135, Iran.
Background: Sex reassignment surgery (SRS) is a necessary step in transitioning into the desired gender for male-to-female transgender individuals. This study focuses on a rare complication developed following SRS, aiming to highlight potential complications associated with this procedure.
Case Presentation: This report describes a 49-year-old transgender woman with a history of SRS who developed bloody diarrhea and neovaginal bleeding 10 years later.
Sheikhmoonesi, F. (2024) "Male-to-female and female-to-male transsexual siblings with pedophilic father: A case report" , 12: e8580. https://doi.
View Article and Find Full Text PDFCross-Cultural Adaptation and Face Validation of the Chilean Version of the Operated Male to Female Sexual Function Index.
Int Urogynecol J
June 2024
Facultad de Medicina, Clínica Alemana, Universidad del Desarrollo, Avenida Plaza 680, Las Condes, Santiago, Chile.
Article Synopsis
- Transgender and gender-diverse individuals often face discrimination in medical settings, but gender-affirming treatments, like genital-affirming surgery, can enhance their quality of life; however, sexual function assessments after such surgeries have typically used tools meant for those assigned female at birth, leading to inaccuracies.
- The study involved translating and adapting the Male to Female Sexual Function Index (oMtFSFI) into Spanish for Chilean transgender women, testing its face validity through input from eight participants.
- Feedback indicated that while the questionnaire effectively evaluated sexual function, some terminology was confusing, and assumptions regarding partner presence and penetrative intercourse needed reconsideration, leading to an agreement on necessary adaptations based on patient perspectives.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!