Research spanning multiple domains of psychology has demonstrated preferential processing of animate as compared to inanimate entities--a pattern that is commonly explained as due to evolutionarily adaptive behavior. Forces of nature represent a class of entities that are semantically inanimate but which behave as if they are animate in that they possess the ability to initiate movement and cause actions. We report an eye-tracking experiment demonstrating that natural forces are processed like animate entities during online sentence processing: they are easier to integrate with action verbs than instruments, and this effect is mediated by sentence structure. The results suggest that many cognitive and linguistic phenomena that have previously been attributed to animacy may be more appropriately attributed to perceived agency. To the extent that this is so, the cognitive potency of animate entities may not be due to vigilant monitoring of the environment for unpredictable events as argued by evolutionary psychologists but instead may be more adequately explained as reflecting a cognitive and linguistic focus on causal explanations that is adaptive because it increases the predictability of events.
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http://dx.doi.org/10.1016/j.cognition.2014.11.021 | DOI Listing |
Phys Rev Lett
December 2024
School of Physics and Astronomy, Institute of Natural Sciences and MOE-LSC, Shanghai Jiao Tong University, Shanghai 200240, China.
Chemically driven micromotors exhibit a pronounced affinity for nearby surfaces, yet the quantification of this motor-wall interaction strength remains unexplored in experiments. Here, we apply an external force to a self-electrophoretic micromotor which slides along a wall and measures the force necessary to disengage the motor from the wall. Our experiments unveil that the required disengaging force increases with the strength of chemical driving, often surpassing both the motor's effective gravity and its propulsive thrust.
View Article and Find Full Text PDFNeurochem Res
January 2025
Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, China.
Depression is a common and complex neuropsychiatric disorder affecting people of all ages worldwide, associated with high rates of relapse and disability. Neohesperidin (NEO) is a dietary flavonoid with applications in therapeutics; however, its effects on depressive-like behavior remain unknown. Here, we evaluated the effects of NEO on depressive-like behavior induced by chronic and unpredictable mild stress (CUMS).
View Article and Find Full Text PDFAging Dis
December 2024
Department of Biomechanics, Poznan University of Physical Education, Poznań, Poland.
This review summarizes the mechanism and role of physical activity in maintaining the proper functioning of the musculoskeletal system. Bone adaptation to the mechanical environment occurs in skeletal regions subjected to the greatest stresses resulting from the nature of exercise, however, there is a varied response of bone tissue to mechanical loads depending on its material and structural properties (trabecular and cortical). The regulation of bone tissue metabolism during physical exercise is influenced by factors associated with mechanical stress (gravitational forces, impact loading, and muscular contractions) as well as by systemic mechanisms (hormones, myokines, cytokines).
View Article and Find Full Text PDFIntegr Psychol Behav Sci
January 2025
Department of Psychology, St. Petersburg State University, St. Petersburg, Russian Federation.
The paper analyzes current discussions concerning the so called "replicability crisis" - a notion describing difficulties in attempts to confirm existing research findings by their additional scrutiny or by new empirical studies. We propose interpretation that this "crisis" may be seen as a manifestation of the increasing inconsistency between, on the one hand, the outdated views on a human being and social structures dominating in the academic mainstream across various disciplines, including psychology and sociology, and, on the other hand, the reality of the emerging new stage of societal evolution, neo-structuration, which brings to the forefront individual agency. Our analysis suggests the possibilities for the future inter-disciplinary paradigmatic shift, which implies putting in the center of research not the idea of a constant or predictably developing individual in the context of solid external structures operating in line with a presumably sustainable "progress".
View Article and Find Full Text PDFJ Mol Model
January 2025
Laboratorio de Química Teórica Computacional (QTC), Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Avenida Vicuña Mackenna 4860, 7820436, Santiago de Chile, Chile.
Context: Dopamine -monooxygenase (D M) is an essential enzyme in the organism that regioselectively converts dopamine into R-norepinephrine, the key step of the reaction, studied in this paper, is a hydrogen atom transfer (HAT) from dopamine to a superoxo complex on D M, forming a hydroperoxo intermediate and dopamine radical. It was found that the formation of a hydrogen bond between dopamine and the D M catalyst strengthens the substrate-enzyme interaction and facilitates the HAT which takes place selectively to give the desired enantiomeric form of the product. Six reactions leading to the hydroperoxo intermediate were analyzed in detail using theoretical and computational tools in order to identify the most probable reaction mechanism.
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