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Effect of a dosing-time on quetiapine-induced acute hyperglycemia in mice.
J Pharmacol Sci
March 2017
Division of Clinical Pharmacology, Department of Pharmacology, School of Medicine, Jichi Medical University, Shimotsuke, Japan. Electronic address:
Although rare, second-generation antipsychotic drugs cause severe hyperglycemia within several days after the initiation of therapy. Because glucose tolerance exhibits circadian rhythmicity, we evaluated an effect of a dosing-time on quetiapine-induced acute hyperglycemia in mice. A single intraperitoneal dose of quetiapine dosing-time-independently induced insulin resistance in fasted C57BL/6J mice.
View Article and Find Full Text PDFQuetiapine-induced hyperglycemic crisis and severe hyperlipidemia: a case report and review of the literature.
Psychosomatics
October 2016
Department of Psychiatry, University of Michigan, Ann Arbor, MI.
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