AI Article Synopsis
- - A minority of asthma patients experience 'severe refractory asthma,' which does not respond well to standard treatments.
- - New therapies are being developed that focus on specific biological targets, including monoclonal antibodies and bronchodilators.
- - Tailoring treatment to the individual patient's inflammatory subtype and symptoms is crucial for effectively managing severe asthma.
Article Abstract
A small percentage of asthmatics have 'severe refractory asthma', where there is suboptimal response to currently available therapies. A number of novel therapies targeting key biological targets are becoming available. Asthma is a heterogeneous disease, and systematic evaluation of patients is important to target therapies to the underlying inflammatory subtype and clinical features. This review article outlines new and emerging treatments for severe asthma, including monoclonal antibodies targeting eosinophilic disease, anti-neutrophil strategies, novel bronchodilators and bronchial thermoplasty. We highlight the importance of individualized investigation, treatment and management of severe asthmatics.
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| http://dx.doi.org/10.1177/1479972314562210 | DOI Listing |
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