In a current study, a distinctive voltammetric method was developed for the determination of uric acid (UA) at a carbon paste electrode (CPE) modified with zinc oxide nanofibers (ZNFs) and quercetin (Q). ZNFs were fabricated via the electrospinning process. The electrode was prepared by electrodeposition of quercetin on a zinc oxide nanofiber carbon paste electrode (Q/ZNFs/CPE). The Q/ZNFs/CPE offered substantially lower overpotential for electro-oxidation of UA in acetate buffer solution (ABS) (pH 4.45) compared with Q/CPE, ZNFs/CPE and bare CPE. Furthermore, the effects of pH, scan rate, accumulation time and potential, interference effect and effect of quercetin electrodeposition on the surface of ZNFs/CPE were studied in detail. The studies suggested that the electrode reaction process was totally irreversible and adsorption controlled. Differential pulse voltammogram peak current of UA increased linearly with its concentration within two dynamic ranges and detection limit for UA was 0.05 μmol L(-1) with RSD=0.2%. The prepared electrode was applied for determination of UA levels in serum and plasma of a healthy person and the patient with leukemia. The results indicated that the proposed method was sensitive, selective, fast and simple for determination of UA.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.msec.2014.10.060 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Advancing cancer therapy with custom-built alternating electric field devices.
Bioelectron Med
January 2025
School of Pharmacy, Biodiscovery Institute & Boots Science Building, University of Nottingham, Nottingham, NG7 2RD, UK.
Background: In glioblastoma (GBM) therapy research, tumour treating fields by the company Novocure™, have shown promise for increasing patient overall survival. When used with the chemotherapeutic agent temozolomide, they extend median survival by five months. However, there is a space to design alternative systems that will be amenable for wider use in current research.
View Article and Find Full Text PDFFish active packaging with ZnO/Fe-MMT nanoparticles.
Sci Rep
January 2025
Nanotechnology Department, Faculty of Science, Urmia University, Urmia, Iran.
Today, active packaging has become essential to increase food safety and decrease food spoilage. In this study, the aim was to delay spoilage and increase the shelf life of rainbow fish fillets with a new hybrid nanocomposite active packaging. Packaging was fabricated with Ethylene vinyl acetate and active compounds such as rosemary extract, zinc oxide nanoparticles, and modified iron (Fe-MMT).
View Article and Find Full Text PDFAntimicrobial and antibiofilm activity of prepared thymol@UIO-66 and thymol/ZnONPs@UIO-66 nanoparticles against Methicillin-resistant Staphylococcus aureus: A synergistic approach.
Colloids Surf B Biointerfaces
January 2025
Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:
This study introduces a novel approach to enhance the antibacterial properties of UIO-66 by incorporating both Thymol and ZnO nanoparticles within its framework which represents a significant advancement like exhibiting a synergistic antibacterial effect, providing a prolonged and controlled release, and mitigating cytotoxicity associated with the release of free ZnO nanoparticles by combining these two antimicrobial agents within a single, well-defined metal-organic framework. UIO-66 frameworks are investigated as carriers for the natural antimicrobial agent, Thymol, and ZnONPs offering a novel drug delivery system for antibacterial applications. Results demonstrated 132, 90, 184, and 223 nm sizes for UIO-66, ZnONPs, UIO-66 encapsulated Thymol, and UIO-66 encapsulated both Thymol and ZnONPs, respectively.
View Article and Find Full Text PDFEco-friendly zinc oxide nanoparticle biosynthesis powered by probiotic bacteria.
Appl Microbiol Biotechnol
January 2025
School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW, 2308, Australia.
The rapid advancement of nanotechnology, particularly in the realm of pharmaceutical sciences, has significantly transformed the potential for treating life-threatening diseases. A pivotal aspect of this evolution is the emergence of "green nanotechnology," which emphasizes the environmentally sustainable synthesis of raw materials through biological processes. This review focuses on the biological synthesis and application of zinc oxide (ZnO) nanoparticles (NPs) from probiotic bacteria, particularly those sourced from wastewater.
View Article and Find Full Text PDFPutting Charge Transfer Degree as a Bridge Connecting Surface-Enhanced Raman Spectroscopy and Photocatalysis.
Angew Chem Int Ed Engl
January 2025
Jilin University, State Key Laboratory of Supramolecular Structure and Materials, 2699 Qianjin Street, 130012, Changchun, CHINA.
To date, few systematic approach has been established for predicting catalytic performance by analyzing the spectral information of molecules adsorbed on photocatalyst surfaces. Effective charge transfer (CT) between the semiconductor photocatalysts and surface-absorbed molecules is essential for enhancing catalytic activity and optimizing light energy utilization. This study aimed to validate the surface-enhanced Raman spectroscopy (SERS) based on the CT enhancement mechanism in investigating the CT process during semiconductor photocatalytic C-C coupling model reactions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!