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Impact of potentially inappropriate medications on emergency ambulance admissions in geriatric patients after discharge.
Pharmazie
December 2024
Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan.
This study aimed to determine the risk of emergency admission by ambulance in patients taking potentially inappropriate medications (PIMs). We included 273,932 patients aged over 75 years of age admitted between January 1, 2019, and December 31, 2019, using the Japan Medical Data Center medical insurance database containing anonymized patient data. We excluded patients without a history of admission.
View Article and Find Full Text PDFEffectiveness of Buspirone in Alleviating Anxiety Symptoms in Patients with Depressive Disorder: A Multicenter Prospective Observational Study in Korea.
Clin Psychopharmacol Neurosci
February 2025
Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Objective: We aimed to investigate the effectiveness of buspirone as an adjunctive therapy for alleviating anxiety symptoms in patients with depressive disorders who are already taking antidepressants.
Methods: This was an open-label prospective multicenter non-interventional observational study conducted over 12 weeks. We enrolled 180 patients diagnosed with depressive disorders according to DSM-5 criteria and Hamilton Anxiety Rating Scale (HAMA) scores ≥ 18.
Drug overdose deaths among women 1999-2021 in the United States: Differences by race, ethnicity, and age.
Womens Health (Lond)
December 2024
Department of Human Development and Family Studies and Family Studies, The Pennsylvania State University, University Park, PA, USA.
Background: The U.S. drug overdose epidemic is increasingly severe and steep increases have been seen among women.
View Article and Find Full Text PDFThe Effects of Prescribed Medications on Depressive Symptoms and Neurocognitive Performance in People With Human Immunodeficiency Virus (HIV).
Clin Infect Dis
December 2024
Department of Medicine, University of California, San Diego, California, USA.
Background: Alterations in brain function and structure, such as depression and neurocognitive impairment, continue to occur in people with human immunodeficiency virus (HIV, PWH) taking suppressive antiretroviral therapy (ART). The lifespan of PWH has improved but the healthspan remains worse than people without HIV, in part because of aging-related diseases. As a result, polypharmacy is common and increases the risk of drug-drug interactions and adverse reactions.
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