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Do cytokines play a role in the transition from acute to chronic musculoskeletal pain?
Pharmacol Res
January 2025
University Hospital of Jena, Institute of Physiology 1, D-07740 Jena, Germany. Electronic address:
Musculoskeletal pain has a high prevalence of transition to chronic pain and/or persistence as chronic pain for years or even a lifetime. Possible mechanisms for the development of such pain states are often reflected in inflammatory or neuropathic processes involving, among others, cytokines and other molecules. Since biologics such as blockers of TNF or IL-6 can attenuate inflammation and pain in a subset of patients with rheumatoid arthritis, the question arises to what extent cytokines are involved in the generation of pain in human musculoskeletal diseases.
View Article and Find Full Text PDF"Modified arthroscopic disc repositioning and suturing technique for the treatment of TMJ anterior disc displacement without reduction: A technical note".
J Craniomaxillofac Surg
January 2025
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China. Electronic address:
Anterior disc displacement without reduction (ADDwoR) is one of the most common types temporomandibular disorders (TMD), which is often characterized by joint pain, abnormal joint sounds, and limited mouth opening. Disc repositioning has been described as an effective method to reduce joint pain and improve range of motion. Yang's arthroscopic disc repositioning and suturing surgery has been reported to be the most stable technique with 95%-98% of success rate.
View Article and Find Full Text PDFTMJ Metastasis: Evaluation of 3 Patients.
J Craniofac Surg
January 2025
Department of Oral and Maxillofacial Surgery, University Hospital Olomouc and Palacky University Olomouc, Olomouc, Czech Republic.
Metastases of the articular process, temporomandibular joint (TMJ), are rare findings. Their frequency is around 5% of patients with metastatic involvement of the mandible. The most common primary tumor is adenocarcinoma of the lung in women and adenocarcinoma of the prostate in men.
View Article and Find Full Text PDFPrevalence of Temporomandibular Disorder and its association with anxiety in academics: a cross-sectional study.
Sao Paulo Med J
January 2025
Associate Professor, Graduate Program in Dentistry, Atitus Educação, Passo Fundo (RS), Brazil.
Background: Temporomandibular disorders (TMD) are a major cause of non-dental pain in the oral and facial regions.
Objective: This study aimed to determine the prevalence and severity of TMD and anxiety among academics and to investigate the relationship between TMD and its associated factors.
Design And Setting: This cross-sectional study included a sample of 295 academics undertaking health courses at a university in Brazil.
The effect of anterior disc displacement with polycystic ovarian syndrome on adolescent condylar bone remodeling.
BMC Oral Health
January 2025
Department of Oral Surgery, Shanghai Ninth People's Hospital, School of Medicine, College of Stomatology, National Center for Stomatology, Shanghai Key Laboratory of Stomatology, Shanghai Jiao Tong University, Shanghai Jiao Tong University, National Clinical Research Center for Oral Diseases, Shanghai Research Institute of Stomatology, 639 Zhizaoju Road, Shanghai, 200011, China.
Background: Adolescent females have a high prevalence of temporomandibular joint (TMJ) anterior disc displacement (ADD), which can lead to condylar resorption and dentofacial deformity. Polycystic ovarian syndrome (PCOS) is a common endocrine disorder that disrupts bone metabolism. However, the effects of PCOS on bone remodeling especially after disc repositioning (DR) surgery are not well understood.
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