[Study of membranotropic and antioxidant activity of flavonoids and their complexes with ferric iron].

We studied the interaction with liposomes and the antioxidant activity of flavonoid (quercetin, catechin, taxifolin) complexes with iron (III). It was found that the lipophilicity of complexes depends on an iron:flavonoid ratio and grows at a ratio of 1 to 1, while complexes in a 2:1 ratio were the most effective to slow down the lipid peroxidation and restore radical 2,2-diphenyl-1-pic: rylhydrazyl. Thus, the stoichiometry of complexes formed in aqueous solution, may differ from the stoichiometry of complexes that most effectively protect membranes from.peroxidation.