Low inter-arytenoid height: a subclassification of type 1 laryngeal cleft diagnosis and management.

Int J Pediatr Otorhinolaryngol

Department of paediatric otorhinolaryngology, Westmead childrens hospital, Westmead, Sydney, NSW, Australia.

Published: January 2015

Objective: To report our experience of patients with type 1 laryngeal cleft, (including low inter-arytenoid height) who failed conservative management over a five year period. We describe the diagnostic elements of the history, examination at laryngobronchoscopy and provide a management algorithm including the use of inter-arytenoid submucosal injection of gelfoam as a temporary therapeutic as well as diagnostic tool.

Methods: A retrospective case note review over a five year period was undertaken to review all cases of type 1 laryngeal cleft who failed conservative management. Presenting symptoms, diagnostic procedures, surgical interventions and clinical outcomes were reviewed.

Results: Seventeen patients were identified. Chronic cough was the most consistent feature in the history (100%). All patients underwent a microlaryngoscopy with binocular microlaryngeal assessment. Six patients (35%) underwent gelfoam injection; four of these went on to a formal repair. The remaining 11 all had a repair performed without injection. The success of surgical repair was 80% (12/15) however in the other three, all had improvement in symptoms.

Conclusions: Type 1 laryngeal cleft anomalies may extend beyond that described by Benjamin and Inglis. An appropriate history as well as binocular inspection at the time of laryngoscopy is essential. Injection augmentation offers a safe tool in the assessment and management, and endoscopic surgical repair remains the standard for definitive therapy in those that fail conservative management.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2014.10.040DOI Listing

Publication Analysis

Top Keywords

type laryngeal
16
laryngeal cleft
16
conservative management
12
low inter-arytenoid
8
inter-arytenoid height
8
failed conservative
8
year period
8
surgical repair
8
management
6
height subclassification
4

Similar Publications

Purpose: The present study aims at exploring the effect of pitch, loudness, vowel, and voice condition on supraglottic activity among female participants with voice disorders and among female participants with normal voices.

Methods: Forty-four volunteers were recruited. Inclusion criteria for the dysphonic group were: 1) age between 20 and 50 years, 2) reporting at least 1 year-long history of voice problems, 3) moderate or severe dysphonia.

View Article and Find Full Text PDF

CSPG4 overexpression implicates higher risks of recurrence and tumorigenesis after surgical intervention of vocal fold Leukoplakia.

Eur Arch Otorhinolaryngol

January 2025

ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai, 200031, China.

Background: Vocal fold leukoplakia (VFL), a precancerous lesion of the larynx, is characterized by white plaques on the vocal fold mucous membrane. Currently, there are no reliable biomarkers to predict the recurrence and malignant transformation of VFL. Considering chondroitin sulfate proteoglycan 4 (CSPG4) as a biomarker for malignant tumors such as laryngeal squamous cell carcinoma (LSCC), we conducted this cohort study to evaluate the prognostic influence of CSPG4 expression on VFL patients.

View Article and Find Full Text PDF

: The study aims to analyse the factors associated with positive margins and endoscopic understaging in laryngeal carcinoma. It also aims to assess the diagnostic accuracy of Narrow Band Imaging (NBI) in comparison to White Light Endoscopy (WLE) and other diagnostic methods. : In this retrospective comparative cohort analysis, 206 patients who underwent endoscopic laser surgery for T1 and T2a glottic squamous cell carcinoma between 1 January 2016 and 30 April 2023 were included.

View Article and Find Full Text PDF

The Trend in Age-Adjusted Incidence of Head and Neck Cancer in South Korea over the Past 20 Years.

Clin Exp Otorhinolaryngol

January 2025

Department of Otorhinolaryngology - Head and Neck Surgery, Konkuk University College of Medicine, Seoul, South Korea.

Objectives: We aimed to calculate the age-adjusted incidence rate of head and neck cancer (HNC) in South Korea from 1999 to 2020 and investigate the incidence trend of HNC excluding the effect of population aging.

Methods: Data were obtained from the Cancer Registration Statistics Program. All 12 types of HNCs were analyzed.

View Article and Find Full Text PDF

Laryngeal squamous cell carcinoma is a common type of head and neck cancer. This study investigated the role of the TRPM2 channel in doxorubicin (DOX)-induced cell damage in human laryngeal squamous cancer cells (Hep-2). Cells were exposed to various DOX concentrations and the appropriate dose was found.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!