Enteropathy associated T cell lymphoma - a case report of an uncommon extranodal T cell lymphoma.

J Clin Diagn Res

Junior Resident, Department of Pathology, Kasturba Medical College, Manipal University, Manipal, India .

Published: October 2014

Enteropathy associated T cell lymphoma is a rare primary intestinal lymphoma. It is often, but not always associated with celiac disease. Intraepithelial T cells are postulated as the cell of origin. It is a rare disease accounting for fewer than 5% of all gastrointestinal tract lymphomas. Recent studies indicate that EATL consists of two diseases that are morphologically and genetically distinct and differ with respect to their frequency of association with celiac disease. Current WHO classification recognises two subtypes of EATL - type 1 (classic) and type 2, based on morphology and immunophenotype. EATL type 1 is a large cell lymphoma which is more common and is more commonly associated with celiac disease compared to type 2. Most common site of involvement is the small intestine. We report a case of EATL type 1, in a 62-year-old female patient who presented with features of intestinal obstruction. However, she did not have spruce like featutes.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253173PMC
http://dx.doi.org/10.7860/JCDR/2014/9740.4999DOI Listing

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