Fungal keratitis is an infectious disease of the cornea. Lack of suspicion and delayed diagnosis herald the onset of complications often leading to permanent loss of vision or worse, enucleation. While a variety of pathogenic fungi especially non-dermatophyte molds associated with fungal keratitis have been identified, a comprehensive review identifying the Trichophyton spp. has not been completed. Trichophyton spp. is a rare but important entity implicated in fungal keratitis. Case reports from around the world designate it as a dangerous pathogen. Trichophyton spp. implicated in keratitis has not previously been reported and is considerably greater than suggested by incidence studies. Patient outcome is heavily reliant upon correct identification, timely intervention and effective treatment. Species identification, the risk factors associated with, and pathogenesis of keratitis will allow the development of improved therapies. This mini review provides a resource for clinicians and researchers to recognize Trichophyton spp. as a potent etiological agent capable of causing keratitis. It is no more a dermatophyte limited to infection of appendages.
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http://dx.doi.org/10.7860/JCDR/2014/9029.5044 | DOI Listing |
Mycoses
January 2025
Unit of Mycology, Statens Serum Institut, Copenhagen, Denmark.
Background: Emerging terbinafine resistance in Trichophyton species has been reported globally. The prevalence in clinical samples from patients with treatment failure is unknown in Denmark.
Objectives: Prospective study of terbinafine resistance in Trichophyton isolates from patients with recalcitrant skin or nail infections.
Int J Med Mushrooms
December 2024
Laboratory of Fungal Biology and Biotechnology, Yerevan State University, Yerevan, Armenia; Department of Cardiology, Clinic of General and Invasive Cardiology, University Hospital No. 1, Yerevan State Medical University, Yerevan, Armenia.
The study of antimicrobial activity (AMA) of 14 genetically identified dikaryotic strains of red belted medicinal polypore Fomitopsis pinicola isolated from Betula sp. and other deciduous trees, as well as conifers Picea sp. and Abies alba in Russia, France and Italy against test fungi and bacteria is discussed.
View Article and Find Full Text PDFInt Wound J
December 2024
Biofunctional Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
A wide variety of microbial species, including Trichophyton spp., have been detected in diabetic foot ulcers (DFUs). In particular, Trichophyton spp.
View Article and Find Full Text PDFAntibiotics (Basel)
September 2024
Laboratory of Innovation and Cosmeceutical Technology, Department of Pharmaceutical Sciences, Center of Health Sciences, Hospital Universitário de Londrina, Robert Koch Avenue, 60, Londrina 86038-350, Brazil.
J Clin Microbiol
October 2024
CHU Rennes, Laboratoire de parasitologie-mycologie, European ECMM Excellence Center in Medical Mycology, Centre National de Référence pour les mycoses et antifongiques-Laboratoire associé Aspergilloses chroniques, Rennes, France.
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