Myeloid sarcoma: a rare case of an orbital mass mimicking orbital pseudotumor requiring neurosurgical intervention.

Case Rep Neurol Med

Department of Neurological Surgery, College of Medicine at Urbana-Champaign, Carle Foundation Hospital, University of Illinois, 602 West University Avenue, Urbana, IL 61801, USA.

Published: December 2014

AI Article Synopsis

  • A rare case of myeloid sarcoma (MS) is highlighted, characterized as an unusual form of acute myeloid leukemia (AML) that can sometimes present in adults.
  • A 65-year-old male presented with an orbital pseudotumor that required neurosurgery to diagnose MS, which involved decompressing critical areas around the eye.
  • Following surgery, the patient experienced pain relief and improved vision, with pathology confirming MS, prompting a discussion on its neurosurgical significance as a potential initial indicator of AML.

Article Abstract

Objective. A rare case of myeloid sarcoma (MS), previously referred to as granulocytic sarcoma or chloroma, is presented. Representing a unique form of acute myeloid leukemia (AML), MS may rarely occur in adults. Even rarer, MS may occur as the initial presentation of AML. Methods. We report a singular and illustrative case of an orbital pseudotumor mimicking mass in a 65-year-old male as the initial presentation of AML. Results. Neurosurgical intervention was required to establish the definitive diagnosis via right modified orbitofrontozygomatic craniotomy as well as to decompress the optic canal, superior orbital fissure, and orbit. Conclusion. Postoperatively, he reported decreased pain and improvement of his vision. Further examination revealed decreased proptosis and improved extraocular mobility. Pathological findings demonstrated MS. We review the literature and discuss the neurosurgical relevance of MS as the initial presentation of AML.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247931PMC
http://dx.doi.org/10.1155/2014/395196DOI Listing

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