How past experiences reshape behavior is not well understood. In this issue, two studies (Schild et al., 2014; Yu et al., 2014) dissected the molecular mechanisms underlying experience-dependent plasticity in thermosensory behavior. They show that Ca(2+)/calmodulin-dependent kinase I (CaMKI) regulates thermal preferences according to past experience.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301849 | PMC |
http://dx.doi.org/10.1016/j.neuron.2014.11.014 | DOI Listing |
J Affect Disord
March 2025
Compass Pathfinder Ltd (a subsidiary of Compass Pathways plc), London, UK.
Objective: To determine the relationships between psilocybin dose, psychedelic experiences, and therapeutic outcome in treatment-resistant depression.
Methods: For treatment-resistant depression, 233 participants received a single dose of 25, 10, or 1 mg of COMP360 psilocybin (a proprietary, pharmaceutical-grade synthesized psilocybin formulation, developed by the sponsor, Compass Pathfinder Ltd.) with psychological support.
Orthop Surg
December 2024
Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Psychopharmacology (Berl)
December 2024
Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Rationale: There is increasing interest in establishing psychedelic research programs at academic medical centers. However, psychedelics are intensely psychoactive, carry considerable sociopolitical baggage, and most are Schedule I drugs, creating significant potential impediments to implementation. There is little formal guidance for investigators on navigating the complex on-the-ground obstacles associated with establishing psychedelic research programs.
View Article and Find Full Text PDFOmega (Westport)
November 2024
School of Psychology and Vision Sciences, University of Leicester, Leicester, UK.
Home care workers (HCWs) may frequently experience client death. This critical interpretive meta-synthesis aimed to identify the impacts of client death to offer preliminary recommendations with respect to support. Five electronic databases, APA PsycINFO, CINAHL, MEDLINE, Web of Science, and Scopus, were searched systematically using keywords and subject headings.
View Article and Find Full Text PDFDev Med Child Neurol
October 2024
Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Aim: To seek consensus on recommendations for the delivery of services to disabled children in England during future emergencies.
Method: Candidate recommendations were drafted based on our related mapping review and qualitative research related to experiences during the COVID-19 pandemic. Iterative workshops with professionals and parent carers helped to refine the recommendations.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!