AI Article Synopsis
- The NUCABEL study found increased thyroid cancer rates among people living near two Belgian nuclear sites (Mol-Dessel and Fleurus), prompting further investigation.
- Researchers reanalyzed data to explore whether cancer incidence increased with proximity to the nuclear sites and levels of exposure to radioactive discharges.
- Results indicated no significant link for Mol-Dessel, while Fleurus showed borderline significance, suggesting more research is needed, especially since it is a major producer of radio-iodines in Europe.
Article Abstract
Background: In a recent ecological study among residents living around Belgian nuclear sites (the NUCABEL study), significant increased incidences of thyroid cancer were observed around the two nuclear facilities with industrial and research activities (Mol-Dessel and Fleurus), prompting further research.
Methods: The data from the NUCABEL study were reanalysed to test the hypothesis of a gradient in cancer incidence with increasing levels of exposure from these sites using three measures of surrogate exposure, being (i) residential proximity, (ii) prevailing wind directions and (iii) simulated dispersion of radioactive discharges. Single-site focussed hypothesis tests were complemented with Generalized Additive Models to estimate the exposure-response relationships.
Results: For Mol-Dessel, the results of the focussed hypothesis tests were far from significant. For Fleurus, the p-values were much closer to significance with p=0.05 for Bithell's Linear Risk Score using radioactive discharge estimates as surrogate.
Conclusions: The re-analyses refute an association with the nuclear facilities for the site of Mol-Dessel. For the site of Fleurus, one of Europe's major production sites of radio-iodines, the results were less conclusive and further research suggests itself.
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| http://dx.doi.org/10.1016/j.canep.2014.10.011 | DOI Listing |
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