In most countries, their regulatory bodies which control food, drugs, and cosmetics are responsible for regulating all the color additives to ensure that they are safe with those products, ensuring that they contain only approved ingredients, and that they are accurately labeled. Permitted colors are subject to rigorous safety standards prior to their approval and prior to the release of their specific use. Although a colorant may have approval in several countries, its use, level of use, specifications, acceptance criteria, and labeling requirements may differ from one country to another. In this review, we have explored the legislative and regulatory framework regarding the color additives for use in drugs and cosmetics.

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