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| http://dx.doi.org/10.1371/journal.pntd.0003290 | DOI Listing |
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Disseminated nocardiosis in a patient with AIDS and B-cell non-Hodgkin's lymphoma: a case report.
BMC Infect Dis
January 2025
Department of Infectious Diseases, Hospital Universitario de Caracas, Caracas, Venezuela.
Background: Disseminated nocardiosis is a rare and potentially fatal disease, with a higher incidence in immunocompromised patients, such as those living with human immunodeficiency virus (HIV) or hematological malignancies, including lymphoma. Information on Nocardia spp. infection in Venezuela is limited.
View Article and Find Full Text PDFExperiences and perspectives on rapid-test diagnosis of tuberculosis, histoplasmosis and cryptococcosis in people with advanced HIV/AIDS disease in Porto Alegre, Brazil.
PLoS One
November 2024
Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
The rapid diagnosis of opportunistic infections (OIs) is critical for improving the health outcomes of people living with HIV/AIDS (PLWHA). This study aimed to describe the feasibility of implementing a package for the rapid diagnosis of tuberculosis, histoplasmosis, and cryptococcosis in patients with advanced HIV/AIDS disease in Porto Alegre, Brazil. The research involved two focus groups with health professionals, four in-depth interviews with healthcare managers, and twelve interviews with PLWHA.
View Article and Find Full Text PDFPatterns of Amphotericin B Use and Factors Related to Mortality in a Low-Middle Income Country: An Observational and Longitudinal Study.
Antibiotics (Basel)
October 2024
Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma S.A., Pereira 660003, Colombia.
Article Synopsis
- Amphotericin B is primarily used to treat deep systemic fungal infections, with a study analyzing its effects on Colombian patients from 2015 to 2022.
- The study found that 40.3% of the 310 patients died during hospitalization, with factors such as higher comorbidity and the need for invasive procedures significantly increasing mortality rates.
- The research highlighted that while conventional amphotericin B was the main treatment, receiving systemic corticosteroids was associated with a lower risk of death.
CNS histoplasmosis coexisting with pulmonary tuberculosis in a HIV negative patient: case report.
BMC Infect Dis
November 2024
Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, India.
Article Synopsis
- Tuberculosis is common in India, while Histoplasmosis is less reported; co-infection is rare but challenging to diagnose due to symptom overlap.
- A 62-year-old man was diagnosed with both conditions, initially treated with appropriate medications, but experienced complications due to drug interactions.
- Follow-up treatment adjustments led to significant improvement, highlighting the need for careful monitoring and awareness of potential drug interactions in similar cases.
From Histoplasmosis to Cryptococcosis: A diagnostic journey of pediatric scalp abscess.
Indian J Med Microbiol
December 2024
Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, 751019, India. Electronic address:
Article Synopsis
- A 3-year-old boy undergoing treatment for disseminated tuberculosis developed scalp swelling, prompting a needle aspirate.
- The aspirate identified yeasts inside macrophages, initially misdiagnosed as Histoplasmosis but later confirmed as Cryptococcosis.
- Treatment with liposomal amphotericin B and fluconazole led to the resolution of lesions, marking this as a rare pediatric case of cryptococcosis from Odisha.
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