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Innovative antifungal strategies: enhanced biofilm inhibition of by a modified tea tree oil formulation.
Front Microbiol
January 2025
Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Prague, Czechia.
Introduction: is a significant human pathogen with the ability to form biofilms, a critical factor in its resistance to antifungal treatments. This study aims to evaluate the antifungal activity and biofilm inhibition potential of Tea Tree Oil (TTO) derived from cultivated in Vietnam.
Methods: The antifungal activity of TTO was assessed by determining the Minimum Inhibitory Concentration (MIC), Minimum Fungicidal Concentration (MFC), Minimum Biofilm Inhibitory Concentration (MBIC), and Minimum Biofilm Eradication Concentration (MBEC) using broth dilution methods.
Comparative Analysis of In-House and Commercially Available Media for Determining the Antifungal Susceptibility Profile of Candida Species.
Cureus
December 2024
Department of Microbiology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed To Be University), Karad, IND.
Background The emergence of treatment-resistant species has highlighted the importance of antifungal susceptibility testing as it is difficult to determine therapeutics solely based on species identification. However, as compared to bacterial pathogens, antimicrobial susceptibility testing in fungi still remains underutilized in most clinical diagnostic microbiological services. The disc diffusion (DD) technique is reported to be easy and cost-effective and therefore can be easily incorporated as a routine method.
View Article and Find Full Text PDFEco-Friendly Synthesis of Selenium Nanoparticles via Sternbergia candida: Enhancing Antioxidant Defense and Mitigating Salt Stress in Pepper (Capsicum annuum L.) Plants.
ChemistryOpen
January 2025
Department of Food Processing, Vocational School of Technical Science, 72060, Batman, Türkiye.
Nanoparticles enhance agricultural applications with their bioactivity, bioavailability, and reactivity. Selenium mitigates the adverse effects of salinity on plant growth, boosting antioxidant defense, metabolism, and resilience to abiotic stress. Our study applied selenium nanoparticles to mitigate salinity-induced damage and support plant growth.
View Article and Find Full Text PDFDynamic analysis of the epidemiology and pathogen distribution of bronchoalveolar lavage fluid in children with severe pulmonary infection: a retrospective study.
Ital J Pediatr
January 2025
Department of Neonatology, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Henan, China.
Background: Severe pulmonary infection is the primary cause of death in children aged < 5 years. The early identification of pathogenic bacteria and targeted anti-infective therapies can significantly improve the prognosis of children with severe infections. This study aims to provide a reference for the rational use of antibiotics at an early stage in children with severe pulmonary infections.
View Article and Find Full Text PDFAntimicrobial activity and applications in PMMA of a novel benzpyrole derivant/iodocuprate hybrid (TMBI)(CuI).
Bioorg Chem
January 2025
Fujian Key Laboratory of Oral Diseases, Fujian Biological Materials Engineering and Technology Center of Stomatology, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, Fujian 350004, China; Department of Prosthodontics, School and Hospital of Stomatology, Fujian Medical University, Fuzhou 350001, China. Electronic address:
Among individuals who wear removable dentures, there is a significant likelihood, reaching up to 70 %, of experiencing a condition known as denture-induced stomatitis. To address this issue, a commonly used method involves soaking dentures in denture cleansers to eliminate microorganisms. However, the prolonged use of this cleaning method has resulted in the emergence of drug resistance.
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