AI Article Synopsis
- - Idiopathic CD4 lymphocytopenia (ICL) is a condition where there are low CD4+ lymphocyte counts not caused by HIV or other diseases.
- - A case is reported of a 57-year-old man with ICL and giant cell arteritis who developed pulmonary mucormycosis, marking a first in medical literature for this combination.
- - Low CD4+ or total lymphocyte counts in autoimmune disorder patients should raise concerns for ICL, and immunosuppressive treatments should be approached with caution.
Article Abstract
Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report of these occurring in a patient with ICL. Abnormally low total lymphocyte or CD4+ cell counts occurring in patients with autoimmune disorders should alert clinicians to the possibility of ICL. Immunosuppressive treatment should be used with caution in this context.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246401 | PMC |
| http://dx.doi.org/10.1016/j.mmcr.2014.10.002 | DOI Listing |
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