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Purloined mechanisms of bacterial immunity can cure muscular dystrophy. | LitMetric

Purloined mechanisms of bacterial immunity can cure muscular dystrophy.

Cell Metab

Department of Neurology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095-1769, USA.

Published: December 2014

Myriad strategies have been explored to compensate for the lack of dystrophin or to skip mutations that cause the lethal disease Duchenne muscular dystrophy (DMD). A new study shows that gene editing strategies used by bacteria can be applied in zygotes of a mouse model of DMD to correct the genetic defect that causes muscular dystrophy (Long et al., 2014).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467519PMC
http://dx.doi.org/10.1016/j.cmet.2014.11.011DOI Listing

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