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Analysis of Short-Term Prognostic Factors of Posterior Single Open-Door Laminoplasty in Patients with Cervical Spondylotic Myelopathy.
Ann Ital Chir
December 2024
Department of Painology, The First People's Hospital of Tongxiang City, 314500 Tongxiang, Zhejiang, China.
Aim: Posterior cervical expansive open-door laminoplasty (ELAP) is one of the main methods for the treatment of multilevel cervical spondylotic myelopathy (CSM). However, some patients are vulnerable to developing complications such as kyphosis and axial symptoms after ELAP, potentially facing adverse prognosis following the procedure. At present, there are few reports on the short-term prognostic factors in Chinese patients with CSM after undergoing ELAP.
View Article and Find Full Text PDFSpinal Dumbbell Meningiomas: A Systematic Review.
Ann Ital Chir
December 2024
Neurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, 95124 Catania, Italy.
Aim: This systematic review aims to synthesize the epidemiology, clinical presentation, diagnostic approaches, treatment strategies, and outcomes of spinal dumbbell meningiomas to enhance understanding and improve patient management.
Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, four major databases (PubMed, Scopus, Web of Science, and Cochrane Library) were searched until June 2024. Studies included patients diagnosed with spinal dumbbell intradural-extradural meningiomas, focusing on patient demographics, tumor characteristics, diagnostic methods, treatment modalities, and clinical outcomes.
Targeting Remyelination in Spinal Cord Injury: Insights and Emerging Therapeutic Strategies.
CNS Neurosci Ther
December 2024
Central Laboratory of The Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People's Hospital, Lishui, Zhejiang, China.
Introduction: Spinal cord injury (SCI) is a severe neurological disease characterized by significant motor, sensory, and autonomic dysfunctions. SCI is a major global disability cause, often resulting in long-term neurological impairments due to the impeded regeneration and remyelination of axons. A SCI interferes with communication between the brain and the spinal cord networks that control neurological functions.
View Article and Find Full Text PDFTrehalose Cryopreservation of Human Mesenchymal Stem Cells from Cord Tissue.
Biopreserv Biobank
December 2024
Coordinating Node, Andalusian Public Health System Biobank, Granada, Spain.
Adequate hypothermic storage of human mesenchymal stem cells (hMSCs) is of fundamental importance since they have been explored in several regenerative medicine initiatives. However, the actual clinical application of hMSCs necessitates hypothermic storage for long periods, a process that requires the use of non-toxic and efficient cryo-reagents capable of maintaining high viability and differentiating properties after thawing. Current cryopreservation methods are based on cryoprotectant agents (CPAs) containing dimethylsulphoxide (DMSO), which have been shown to be toxic for clinical applications.
View Article and Find Full Text PDFNitrous oxide (NO) is generally used in the medical and food industries. However, it is sometimes illegally misused by young adults as a recreational drug. In either of these uses, functional vitamin B12 deficiency results in neurological implications, such as peripheral neuropathy and subacute combined degeneration (SACD).
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