AI Article Synopsis

  • A study of 112 patients with ischemic heart disease and type 2 diabetes mellitus compared the effectiveness of everolimus eluting stents (EES) to sirolimus eluting stents (SES) during percutaneous coronary interventions.
  • Both groups showed similar rates of repeat target lesion revascularizations (5.5% for EES and 8.6% for SES), acute myocardial infarctions (3.7% and 5.2%), and deaths (1.85% and 1.7%).
  • Overall, there were no significant differences in unfavorable cardiac events or stent thrombosis rates between the two groups, indicating that EES and SES are equally effective in this patient population.

Article Abstract

We included into this study 112 patients with ischemic heart disease (IHD) and concomitant type 2 diabetes mellitus (DM) subjected to percutaneous coronary interventions with stenting. Everolimus and sirolimus eluting stents (EES and SES) were implanted in 54 (group 1) and 58 (group 2) patients, respectively. After 12 months in groups 1 and 2 rates of repeat target lesion revascularizations (TLR) were 5.5 and 8.6% (odds ratio - OR - 0.62, 95% confidence interval - CI - 0.14- 2.74, p = 0.72); acute myocardial infarctions (MI) - 3.7 and 5.2% (OR 0.71, 95% CI 0.11- 4.4, p = 0.94); deaths - 1.85 and 1.7% (OR 1.1, 95% CI 0.1- 17.6, p = 1.0), respectively. There was no significant difference between groups by rate of unfavorable cardiac events (composite of cardiac death, nonfatal MI, and clinically indicated TLR) - 11.1 and 15.5% in groups 1 and 2, respectively (OR 0.68, 95% CI 0.225- 2.059, p = 0.69). Rates of stent thrombosis also did not differ (1.85 and 3.4% in groups 1 and 2, respectively; OR 0.53, 95% CI 0.05- 6.0; p = 0.94). Thus the use of EES and SES in patients with IHD and type-2 DM was equally effective.

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Source
http://dx.doi.org/10.18565/cardio.2014.8.4-9DOI Listing

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