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Computational hemodynamic indices to identify Transcatheter Aortic Valve Implantation degeneration.

Comput Methods Programs Biomed

February 2025

Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCSS, via Carlo Parea 4, Milan, 20138, Italy; Department of Biomedical, Surgical and Dental Sciences, Università degli studi di Milano, Via della Commenda 10, Milan, 20122, Italy.

Background And Objectives: Structural Valve Deterioration (SVD) is the main limiting factor to the long-term durability of the bioprosthetic valves used for Transcatheter Aortic Valve Implantation (TAVI), a minimally invasive technique for the treatment of severe aortic stenosis. The aim of this retrospective study is to perform patient-specific computational analyses of blood dynamics shortly after TAVI to identify hemodynamic indices that correlate with a premature onset of SVD which is detected at 5-10 years long-term follow-up exam after TAVI.

Methods: The study population comprises fourteen patients: seven cases with SVD at long-term follow-up were identified and seven cases without SVD were randomly extracted from the same cohort.

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Purpose: Protocol description for renal perfusion study using thermographic technology and description of the thermographic and clinical behavior of the transplanted kidneys before and after unclamping.

Methods: Infrared thermographic images of renal grafts are obtained before kidney reperfusion, 10 min after and just before closing the surgical wound. Thermographic data is evaluated together with the type of graft and donor, cold ischemia time, hypovascularized areas determined by the surgeon during surgical intervention, alterations in vascular flow in postoperative echo-Doppler, time at the beginning of graft function and serum creatinine monitoring during postoperative follow-up.

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Background: To verify whether the severity of coronary stenosis could be non-invasively assessed by enhanced transthoracic coronary echo Doppler in convergent color Doppler mode (E-Doppler TTE) over a wide range of values (from mild to severe).

Methods: Color-guided pulsed wave Doppler sampling in the left anterior descending coronary artery (LAD) was performed in 103 diseased LAD segments (corresponding to 94 patients examined) as assessed by quantitative coronary angiography (QCA) or intracoronary ultrasound (IVUS). The E-Doppler TTE examinations consisted of measuring the velocity (vel) at the stenosis site and a reference adjacent segment.

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Article Synopsis
  • Cardiac index (CI) assessments are important in critical care for understanding shock and managing treatment, and echocardiographic methods like CW-VTI and PW-VTI are non-invasive alternatives to traditional methods like thermodilution with PiCCO.
  • A study involving 52 patients in an intensive care unit compared these three methods for measuring CI and found that while CW-VTI and PW-VTI gave lower CI values than PiCCO, CW-VTI was generally closer to PiCCO's measurements.
  • The results indicated that none of the Doppler methods were reliably accurate when considering a percentage error cutoff of 30%, suggesting a need for caution when interpreting CI from these methods.
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Echo Doppler Parameters of Diastolic Function.

Curr Cardiol Rep

April 2023

Section of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.

Purpose Of Review: The purpose of this review is to highlight the echo Doppler parameters that form the cornerstone for the evaluation of diastolic function as per the guideline documents of the American Society of Echocardiography (ASE) and the European Association of Cardiovascular Imaging (EACVI). In addition, the individual Doppler-based parameters will be explored, with commentary on the rationale behind their use and the multi-parametric approach to the assessment of diastolic dysfunction (DD) using echocardiography.

Recent Findings: Previous guidelines for assessment of diastolic function are complex with modest diagnostic performance and significant inter-observer variability.

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