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A Case of Ulcerative Colitis with Acute Pericarditis after Dose Escalation of Mesalazine.
Intern Med
December 2024
Department of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Mesalazine-induced pericarditis is rare, and most cases occur at the time of treatment initiation. A 30-year-old man with ulcerative colitis who had experienced remission for 2 years with mesalazine 2,000 mg/day subsequently experienced relapse. Therefore, the mesalazine dose was increased to 4,000 mg.
View Article and Find Full Text PDFMesalazine-induced myocarditis in a patient with ulcerative colitis: a case report.
Eur Heart J Case Rep
September 2024
Department of Cardiology, St George's Hospital, Blackshaw Road, London SW17 0QT, United Kingdom.
Background: Mesalazine is an established first-line therapy for inflammatory bowel disease (IBD) and remains the mainstay of treatment for mild to moderate ulcerative colitis (UC). Both mesalazine and UC are rare but recognized causes of myopericarditis. Cardiac magnetic resonance (CMR) is a non-invasive method of assessing for myopericarditis.
View Article and Find Full Text PDFMesalazine-induced myopericarditis: a case series.
Eur Heart J Case Rep
September 2023
Division of Structural Interventional Cardiology, University Hospital Careggi, Largo Brambilla 3, 50133 Florence, Italy.
Background: Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the gastrointestinal tract but can have multiorgan involvement. Mesalazine (5-ASA) is a key therapeutic agent in IBD. Mesalazine has rare but potentially life-threatening side effects such as cardiac injury.
View Article and Find Full Text PDFMesalazine-induced esophageal ulcers. A rare adverse effect.
Rev Esp Enferm Dig
May 2024
Aparato Digestivo, Hospital Universitario Son Espases, España.
31-year-old woman. Diagnosis of ulcerative proctitis in February/2022. Calprotectin 1832 μg/g.
View Article and Find Full Text PDFMesalazine-Induced Interstitial Nephritis in a Patient With Ulcerative Colitis.
Cureus
December 2022
Internal Medicine, Centro Hospitalar e Universitário de São João, Porto, PRT.
Acute interstitial nephritis (AIN) corresponds to a decline in kidney function due to an injury induced by drugs (in the majority of cases), infections, and autoimmune disorders. It is characterized by the presence of an interstitial inflammatory infiltrate in the kidney. Here, we describe a case of a man with a previous medical history relevant to ulcerative colitis (UC) who was admitted due to acute kidney injury (AKI) in the setting of AIN secondary to mesalazine.
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