chinmo Mutant fly testis stem cells switching sex farewell to maleness.

Dev Cell

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address:

Published: November 2014

Maintaining cellular identity is crucial for homeostasis, and sexual fates of vertebrate testis and ovary cells require continual reinforcement. In this issue of Developmental Cell, Ma et al. (2014) provide insights into stem cell fate maintenance in Drosophila, finding that the JAK/STAT target chinmo prevents transformation of testis somatic stem cells into their ovarian counterparts.

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http://dx.doi.org/10.1016/j.devcel.2014.11.001DOI Listing

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