Objective: Using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI), our goal was to correlate quantifiable measures of endolymphatic hydrops (EH) with auditory function in the setting of Meniere's disease (MD).

Materials And Methods: Forty-one ears were analyzed in 21 subjects (12 ears with MD, 29 without MD). Vestibular endolymphatic space size measurements obtained with two different techniques were referenced against clinical data.

Results: EH was better evaluated on 3D maximum intensity projections (MIPs) than on two-dimensional (2D) images. Using MIPs, quantitative assessments EH correlated with severity of hearing impairment.

Conclusion: 3D MIPs were superior to 2D images for evaluating EH in the setting of MD.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinimag.2014.09.014DOI Listing

Publication Analysis

Top Keywords

meniere's disease
8
measures endolymphatic
8
endolymphatic hydrops
8
delayed intravenous
4
intravenous contrast-enhanced
4
contrast-enhanced flair
4
flair mri
4
mri meniere's
4
disease correlation
4
correlation quantitative
4

Similar Publications

Surgical treatment of Meniere's disease.

Sci Bull (Beijing)

January 2025

Department of Otolaryngology Head and Neck Surgery & Audiology and Neurotology, Karolinska University Hospital, Stockholm 17176, Sweden.

View Article and Find Full Text PDF

Purpose: To compare vestibulo-ocular reflex (VOR) gain values, gain symmetry between the semicircular canals (SCCs), and saccadic parameters in patients with a nosological diagnosis of Ménière's disease (MD) and vestibular migraine (VM).

Methods: Observational, descriptive, cross-sectional, retrospective study, approved by the Research Ethics Committee, under evaluation report number 4.462.

View Article and Find Full Text PDF

Background: Meniere's disease arises when an abnormal fluid accumulation results in heightened pressure within the inner ear or labyrinth. Its symptoms encompass vertigo, tinnitus, hearing loss, and a sensation of fullness in the ear. Various triggers for Meniere's disease are known, from smoking and alcohol consumption to recent viral illnesses, allergies, and anxiety.

View Article and Find Full Text PDF

FAM136A deficiency has been associated with Ménière's disease. However, the underlying mechanism of action of this protein remains unclear. We hypothesized that FAM136A functions in maintaining mitochondria, even in HepG2 cells.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!