Objective: Using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI), our goal was to correlate quantifiable measures of endolymphatic hydrops (EH) with auditory function in the setting of Meniere's disease (MD).
Materials And Methods: Forty-one ears were analyzed in 21 subjects (12 ears with MD, 29 without MD). Vestibular endolymphatic space size measurements obtained with two different techniques were referenced against clinical data.
Results: EH was better evaluated on 3D maximum intensity projections (MIPs) than on two-dimensional (2D) images. Using MIPs, quantitative assessments EH correlated with severity of hearing impairment.
Conclusion: 3D MIPs were superior to 2D images for evaluating EH in the setting of MD.
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http://dx.doi.org/10.1016/j.clinimag.2014.09.014 | DOI Listing |
J Clin Med
January 2025
Otorhinolaryngology and Head and Neck Surgery Department, University Medical Centre Utrecht, PB 85500, 3508 GA Utrecht, The Netherlands.
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View Article and Find Full Text PDFSci Bull (Beijing)
January 2025
Department of Otolaryngology Head and Neck Surgery & Audiology and Neurotology, Karolinska University Hospital, Stockholm 17176, Sweden.
Codas
January 2025
Programa Associado de Pós-graduação em Fonoaudiologia (Mestrado) - PPgFon, Universidade Federal do Rio Grande do Norte - UFRN - Natal (RN), Brasil.
Purpose: To compare vestibulo-ocular reflex (VOR) gain values, gain symmetry between the semicircular canals (SCCs), and saccadic parameters in patients with a nosological diagnosis of Ménière's disease (MD) and vestibular migraine (VM).
Methods: Observational, descriptive, cross-sectional, retrospective study, approved by the Research Ethics Committee, under evaluation report number 4.462.
J Med Case Rep
January 2025
Centers for Advanced Ent, Woodbridge, VA, US.
Background: Meniere's disease arises when an abnormal fluid accumulation results in heightened pressure within the inner ear or labyrinth. Its symptoms encompass vertigo, tinnitus, hearing loss, and a sensation of fullness in the ear. Various triggers for Meniere's disease are known, from smoking and alcohol consumption to recent viral illnesses, allergies, and anxiety.
View Article and Find Full Text PDFFEBS Open Bio
January 2025
Department of Medical Technology, Faculty of Health Sciences, Kumamoto Health Science University, Kumamoto, Japan.
FAM136A deficiency has been associated with Ménière's disease. However, the underlying mechanism of action of this protein remains unclear. We hypothesized that FAM136A functions in maintaining mitochondria, even in HepG2 cells.
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