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http://dx.doi.org/10.1016/j.amjsurg.2014.07.006 | DOI Listing |
Cognition
January 2025
Minerva Fast Track Group Milestones of Early Cognitive Development, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstraße 1A, 04103 Leipzig, Saxony, Germany; Department of Liberal Arts and Sciences, University of Technology Nuremberg, Ulmenstraße 52i, 90443 Nuremberg, Germany. Electronic address:
As social beings, we excel at understanding what other people think or believe. We even seem to be influenced by the belief of others in situations where it is irrelevant to our current tasks. Such altercentric interference has been proposed to reflect implicit belief processing.
View Article and Find Full Text PDFPharmacoeconomics
January 2025
Division of Pulmonology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Shengli Road, Tainan, 704, Taiwan.
Background And Objective: Approximately half of lung adenocarcinomas in East Asia harbor epidermal growth factor receptor (EGFR) mutations. EGFR testing followed by tissue-based next-generation sequencing (NGS), upfront tissue-based NGS, and complementary NGS approaches have emerged on the front line to guide personalized therapy. We study the cost effectiveness of exclusionary EGFR testing for Taiwanese patients newly diagnosed with advanced lung adenocarcinoma.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Treeline Ecological Research, 21551 Twp Rd 520, Sherwood Park, Alberta, T8E 1E3, Canada.
Based on analysis of documents obtained in public databases and under freedom of information requests, this study assessed the Alberta Energy Regulator's (AER) monitoring and management of bitumen tailings spills. The AER's claims of no environmental impacts at any tailings spills lack corroborative environmental data. Claims of perfect spill recovery in 75% of tailings spills are not supported by credible evidence.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Background: In Alzheimer's disease (AD), specific brain regions become vulnerable to pathology while others remain resilient. New methods of imaging such as highly multiplexed immunofluorescence (MxIF) provide an abundance of spatial information, while analytical techniques like machine learning (ML) can address questions of cellular contributors to this regional vulnerability.
Method: We performed MxIF staining for 26 markers and compared postmortem human samples from an AD-susceptible brain area, the prefrontal cortex (PFC, Brodmann's areas 9, 10 or 46) to an AD-resilient brain area, the primary visual cortex (V1, area 17).
Alzheimers Dement
December 2024
Columbia University Irving Medical Center, New York, NY, USA.
Background: Genetic variations have emerged as crucial players in the etiology of Alzheimer's disease (AD), and they serve for a better understanding of the disease mechanisms; yet the specific roles of these genetic variants remain uncertain. Animal models with reminiscent disease pathology could uncover previously uncharacterized roles of these genes. Therefore, we generated zebrafish models for AD variants to analyze the in depth molecular and biological functions of these variants.
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