The evolutionary pathway of specialized metabolism often takes unexpected, perplexing turns. In this issue of Chemistry & Biology, Feng and coworkers provide evidence for a unique phosphatase whose enzymatic product plays a critical role in biofilm formation in Bacillus subtilis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.chembiol.2014.11.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Metagenomic insights into quorum sensing-associated microbial profiling and its correlations with flavor compounds of Maotai-flavor liquor: A case study of stacking fermented grains.
Food Res Int
December 2024
College of Liquor and Food Engineering, Guizhou University, Guiyang 550025, China; Guizhou Provincial Key Laboratory of Fermentation and Biophomacy, Guizhou University, Guiyang 550025, China. Electronic address:
Stacking fermentation is typical process of Maotai-flavor Baijiu and microbial composition determine content of flavors. To date, the knowledge on the driving force of microbial composition was as yet unknown. Since quorum sensing molecule (QSM) plays an important role in modifying microbial interactions.
View Article and Find Full Text PDFPromising and challenging phytochemicals targeting LC3 mediated autophagy signaling in cancer therapy.
Immun Inflamm Dis
October 2024
Department of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, Saudi Arabia.
Background: Phytochemicals possess a wide range of anti-tumor properties, including the modulation of autophagy and regulation of programmed cell death. Autophagy is a critical process in cellular homeostasis and its dysregulation is associated with several pathological conditions, such as cancer, neurodegenerative diseases, and diabetes. In cancer, autophagy plays a dual role by either promoting tumor growth or suppressing it, depending on the cellular context.
View Article and Find Full Text PDFMolecular docking and dynamics simulation of farnesol as a potential anticancer agent targeting mTOR pathway.
In Silico Pharmacol
September 2024
Department of Pharmaceutical Sciences, School of Applied Science and Technology, University of Kashmir, Srinagar, Jammu, Kashmir 190006 India.
Farnesol is a natural acyclic sesquiterpene alcohol, found in various essential oils such as, lemon grass, citronella, tuberose, neroli, and musk. It has a molecular mass of 222.372 g/mol and chemical formula of C₁₅H₂₆O.
View Article and Find Full Text PDFOlfactory stimulation in newborns: Regional differences in cerebral oxygenation.
Brain Res
December 2024
Abteilung für Neonatologie und Intensivmedizin, Department of Pediatrics, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Background: The sense of smell is fully developed in newborns and plays an important role in their early development. There are several approaches to studying olfactory processing in the newborn brain, including EEG, fMRI, and near-infrared spectroscopy (NIRS). Understanding the processing of olfactory stimuli in the newborn brain is of fundamental importance for the development of supportive therapeutic odorant delivery, e.
View Article and Find Full Text PDFMechanisms and Therapeutic Strategies for MAFLD Targeting TLR4 Signaling Pathways.
J Innate Immun
February 2024
Department of Infectious Disease, Liver Disease Center of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Background: Metabolic-associated fatty liver disease (MAFLD) is one of the most common chronic liver diseases. The underlying pathophysiological mechanisms are intricate and involve various factors. Unfortunately, there is currently a lack of available effective treatment options.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!