Randomized controlled trials (RCTs) of interventions intended to modify health behaviors may be influenced by neighborhood effects which can impede unbiased estimation of intervention effects. Examining a RCT designed to increase colorectal cancer (CRC) screening (N=5628), we found statistically significant neighborhood effects: average CRC test use among neighboring study participants was significantly and positively associated with individual patient's CRC test use. This potentially important spatially-varying covariate has not previously been considered in a RCT. Our results suggest that future RCTs of health behavior interventions should assess potential social interactions between participants, which may cause intervention arm contamination and may bias effect size estimation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845650 | PMC |
| http://dx.doi.org/10.1016/j.healthplace.2014.10.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Types and cost of wellness services provided by a neighborhood-based academic nursing center.
Front Public Health
January 2025
Johns Hopkins University School of Nursing, Baltimore, MD, United States.
Background: Despite increased insurance coverage since 2010, racial and ethnic minorities in the United States still receive less medical care than White counterparts. The Johns Hopkins School of Nursing's Center for Community Programs, Innovation, and Scholarship (COMPASS Center) provides free wellness services, aiming to address healthcare disparities in the neighborhoods.
Objective: To delineate the types and cost of wellness services provided by the COMPASS Center.
The Contribution of Adverse Childhood Experiences and Neighborhood Characteristics on Outcomes Experienced by Urban Dwelling Black Men After Serious Traumatic Injury.
J Urban Health
January 2025
School of Nursing, University of Pennsylvania, 418 Curie Blvd, Fagin Hall, Philadelphia, PA, 19104, USA.
Depression and post-traumatic stress disorder (PTSD) are serious consequences of physical injuries. Stress associated with living in urban neighborhoods with socioecological disadvantages and the cumulative burdens of adverse childhood experiences (ACEs) can lead to poorer psychological outcomes. Limited research has explored how ACEs and socioecological environmental exposures in childhood and adulthood, together, impact post-injury outcomes.
View Article and Find Full Text PDFStructural Determinants of School Discipline: Examining State-Level Racial Bias and Neighborhood Opportunity.
J Am Acad Child Adolesc Psychiatry
January 2025
Florida International University, Miami, Florida.
Objective: Addressing the disproportionate use of school detentions and suspensions among Black youth is crucial for reducing educational and health disparities across the lifespan. Yet, few studies have explored external factors beyond school or individual characteristics as potential contributors to school discipline disparities, such as state-level racial bias and neighborhood opportunity.
Method: A subsample from the larger Adolescent Brain Cognitive Development (ABCD) Study® was used (M age at baseline = 9.
Rurality and neighborhood socioeconomic status are associated with overall and cause-specific mortality and hepatic decompensation in type 2 diabetes.
Am J Med
January 2025
Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Veterans Affairs Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA; Gastroenterology Section, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
Introduction: Social determinants of health are key factors driving disease progression. In type 2 diabetes there is limited literature on how distal or intermediate factors (e.g.
View Article and Find Full Text PDFLong-term dynamics of density dependence reveals a more stable effect of the neighborhood on tree growth than tree survival.
PLoS One
January 2025
College of Agriculture and Biological Science, Dali University, Dali, China.
Density dependence is a vital mechanism for explaining tree species diversity. Empirical studies worldwide have demonstrated that neighbor density influences plant survival and growth in various communities. However, it remains unclear how neighbor density affects plant survival and growth over extended periods.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!