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Isolation and characterization of Acinetobacter phage vAbaIN10 active against carbapenem Resistant Acinetobacter baumannii (CRAB) isolates from healthcare-associated infections in Dakar, Senegal.
J Glob Antimicrob Resist
December 2024
Pôle de Microbiologie, Institut Pasteur de Dakar, Sénégal; Faculté de Médecine, Pharmacie et Odontostomatologie, Université Cheikh Anta Diop, Dakar, Sénégal.
Background: Acinetobacter baumannii, particularly carbapenem-resistant strains (CRAB), poses a major concern in the fight against antimicrobial resistance (AMR), identified as a top-priority pathogen by the World Health Organization (WHO). A. baumannii has intrinsic resistance to several antibiotics, including penicillin, cephalosporins, chloramphenicol, and fosfomycin, but the development of AMR has led to the emergence of extremely drug-resistant and pan-resistant isolates.
View Article and Find Full Text PDFReepithelialization of partial thickness porcine burns treated with silver sulfadiazine, triple antibiotic or petrolatum.
Ann Burns Fire Disasters
December 2024
Department of Emergency Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.
Topical antibiotic application and occlusive dressings stand as the current standard of care for partial thickness burn (PTB) treatment. Silver sulfadiazine (SSD) is the most widely used topical antimicrobial agent for acute burn management worldwide. Despite its antimicrobial benefits, there is emerging evidence that SSD might delay wound reepithelialization.
View Article and Find Full Text PDFTwo new strains of Streptomyces with metabolic potential for biological control of pear black spot disease.
BMC Microbiol
December 2024
State Key Laboratory Incubation Base for Conservation and Utilization of Bio-Resource in Tarim Basin, Alar, Xinjiang Uygur Autonomous Region, 843300, China.
Background: Pear black spot is caused by Alternaria tenuissima. It is one of the diseases of concern limiting pear production worldwide. Existing cultivation methods and fungicides are not sufficient to control early blight.
View Article and Find Full Text PDFCharacterization of Enterobacter phage vB_EcRAM-01, a new Pseudotevenvirus against Enterobacter cloacae, isolated in an urban river in Panama.
PLoS One
December 2024
Laboratorio de Microbiología Experimental y Aplicada y Microbiología de Aguas (LAMEXA-LAMA), Universidad de Panamá, Panamá, Panamá.
The Enterobacter cloacae complex, a prominent bacterium responsible worldwide for most bloodstream infections in the hospital environment, has shown broad-spectrum antibiotic resistance, including carbapenems. Therefore, bacteriophages have again attracted the attention of the science and medical community as an alternative to control Multidrug resistant bacteria. In this study, water samples from Río Abajo River, in Panama City, Panama, were collected, for phage isolation, purification, characterization and propagation against the E.
View Article and Find Full Text PDFtargeting of AmpC beta-lactamases in : unveiling Piperenol B as a potent antimicrobial lead.
J Biomol Struct Dyn
December 2024
Department of Biotechnology, School of Bioengineering, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamilnadu, India.
Antimicrobial Resistance poses a major threat to human health worldwide. Microorganisms develop multi-drug resistance due to intrinsic factors, evolutionary chromosomal alterations, and horizontal gene transfer. , a common nosocomial bacterium, can cause various infections and is classified as multidrug-resistant.
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