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Mural nodules and prevalence of high-grade dysplasia in branch duct intraductal papillary mucinous neoplasm of the pancreas undergoing resection.
Br J Surg
November 2024
Centre of Research on Inflammation (CRI), INSERM U1149, Paris, France.
Article Synopsis
- A study was conducted on patients who had surgery for high-risk intraductal papillary mucinous neoplasms (IPMNs) that included a mural module, focusing on the relationship between dysplasia grade and the mural module location.
- The research involved 82 patients, revealing that nearly half had high-grade dysplasia or invasive carcinoma away from the mural module, indicating that local treatment might not be safe or effective.
- The results suggest that pancreatectomy (removal of part or all of the pancreas) remains the best treatment option due to the potential risks associated with localized treatments.
Diagnostic Accuracy of Toluidine Blue Electrospun in Detecting Oral Potentially Malignant Disorders.
Oral Dis
October 2024
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Article Synopsis
- - The study evaluates the effectiveness of toluidine blue (TB)-containing electrospun fibers in detecting oral potentially malignant disorders (OPMDs) with epithelial dysplasia, comparing their performance to traditional histopathological methods.
- - Researchers optimized the concentrations of polyvinylpyrrolidone (PVP) and TB to create fibers and tested them on 36 suspected OPMD lesions, finding that the fibers showed 77.3% sensitivity but only 35.7% specificity in detection.
- - Although the TB-containing fibers demonstrated benefits like easier application and cost-effectiveness for identifying dysplastic changes, their accuracy is not sufficient for standalone diagnosis, suggesting they should be used alongside other diagnostic tools. *
Natural History of the Remnant Pancreatic Duct after Pancreatoduodenectomy for Non-Invasive Intraductal Papillary Mucinous Neoplasm: Results from an International Consortium.
Ann Surg
September 2024
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Background: Little is known about the prognostic significance of pancreatic duct (PD) dilation following pancreatoduodenectomy for intraductal papillary mucinous neoplasms (IPMN). Although PD dilation is typically the hallmark radiographic feature of IPMN, other causes of PD dilation exist, including anastomotic stricture, pancreatitis, senescence, and postsurgical passive dilation. Therefore, PD dilation after pancreatoduodenectomy for IPMN represents a diagnostic and management dilemma.
View Article and Find Full Text PDFEvaluation of anatomical variants and pathological findings of the maxillary sinus prior to sinus floor elevation: A Cone Beam CT retrospective study in 660 patients.
J Clin Exp Dent
June 2024
DDS, MSc, PhD. Professor, Department of Oral Diagnosis and Radiology, Faculty of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
Background: Maxillary sinuses may present a wide spectrum of anatomical variations and pathological lesions whose recognition is mandatory for the clinician, especially prior to any surgical intervention in the area, such as in cases of sinus floor elevation. The goal of this study was the evaluation, mapping and prevalence of sinus anatomical variants and pathoses in Cone Beam Computed Tomography (CBCT) scans of dental patients.
Material And Methods: 660 CBCT examinations of adult patients involving both sinuses were obtained (between 2017 and 2023) and analyzed.
Rapid Growth and Evolution of a Dysplastic Nevus During Pregnancy.
S D Med
December 2023
Department of Internal Medicine, University of South Dakota Sanford School of Medicine.
Article Synopsis
- * Conflicting research exists about how pregnancy affects melanocytic nevi and melanoma, although newer studies suggest that prognosis for pregnant patients with melanoma is not dangerously worse.
- * A case study of a 27-year-old woman highlights the evolution of two moles during her pregnancies, showing that some lesions can change without prior alterations in the intervening periods.
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