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In the thicket of fears, doubts, and murky facts: some reflections on treatment modalities for endometriosis-associated pain.
Hum Reprod
July 2023
Research Institute, Shanghai Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Endometriosis-associated pain can be managed by either surgery or hormonal therapy. The final decision as to which treatment modality to take is based on efficacy and possible complications of different treatment modalities, risk of recurrence, and the patient's wishes and preferences. But in the thicket of fears, doubts, and murky facts, the choice may ultimately be the trade-off between irrational fears and ignorance versus scientific evidence.
View Article and Find Full Text PDFAcute Attack of Pseudogout with the Wide Lesion in Lumbar Spondylolytic Spondylolisthesis.
Case Rep Orthop
July 2020
Department of Orthopedic Surgery, Spinal Injuries Center, Iizuka, Japan.
Article Synopsis
- A case report details an 86-year-old woman who experienced a rare acute attack of calcium pyrophosphate dihydrate (CPPD) deposition disease, specifically pseudogout, manifesting as neurological deficits linked to lumbar spondylolytic spondylolisthesis.
- Diagnostic imaging revealed extensive lesions and effusions in her lumbar region, prompting initial misdiagnosis of pyogenic arthritis before further tests confirmed the presence of crystal deposits.
- Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) led to significant improvement in both her inflammatory and neurological symptoms.
Screening of peripheral arterial disease in primary health care.
Vasc Health Risk Manag
December 2019
Heart and Vascular Center, Department of Vascular Surgery, Semmelweis University, Budapest, Hungary.
Background And Purpose: The screening tool for diagnosing lower extremity arterial disease is the assessment of the ankle-brachial index (ABI), which is widely used in general practice. However, resting ABI can easily produce a false negative result. In light of this, our goal was to determine the proportion of definitive diagnoses (peripheral arterial disease [PAD] confirmed or refuted) among patients screened in general practice, and the rate of cases in which the need for further specialized examination is necessary, with special attention to groups having non-compressible arteries and ABI negative symptomatic status.
View Article and Find Full Text PDFNipah virus: a narrative review of viral characteristics and epidemiological determinants.
Public Health
August 2019
Avalon University School of Medicine (AUSOM), Willemstad, Curacao, Netherlands Antilles. Electronic address:
Objectives: The objectives of this article are to highlight the properties of the Nipah virus (NiV) and discuss its epidemiological determinants.
Study Design: A review of conjectures, epidemiological and clinically related studies, and identification and discussion of preventive approaches is conducted.
Methods: A review of the current literature is performed going through online search engines: PubMed and Google Scholar.
Early earth geodynamics: cross examining the geological testimony.
Philos Trans A Math Phys Eng Sci
October 2018
School of Earth Sciences, University of Western Australia, Perth 6009, Australia
Many studies link the presence of continents on Earth to the operation of plate tectonics. Radiogenic isotope data have, however, long consigned the bulk of crust generation and preservation to the murky realm of the Precambrian Earth, where the prevailing geodynamic systems are highly uncertain due to the sparse and complex nature of the geological record of these early eons. The purpose of this paper is to examine the nature of this geological record, considering the biases and artefacts that may undermine its fidelity, and to assess what are the most robust lines of evidence from which meaningful geodynamic inferences can be drawn.
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