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Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes.
Front Cell Infect Microbiol
January 2023
Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.
Introduction: bacteria cause life-threatening invasive pneumococcal disease (IPD), including meningitis. Pneumococci are classified into serotypes, determined by differences in capsular polysaccharide and both serotype and pneumolysin toxin are associated with disease severity. Strains of serotype 8, ST 53, are increasing in prevalence in IPD in several countries.
View Article and Find Full Text PDFStreptococcus pneumoniae Meningitis Associated With Over-the-Counter Sinus Irrigation.
Cureus
May 2020
Emergency Medicine, Brooke Army Medical Center, San Antonio, USA.
We present the first reported case of bacterial meningitis that may be associated with use of an over-the-counter sinus irrigation. Sinus rinse or "Neti Pot" use is a common remedy for sinus congestion and is felt to be relatively safe. Given its widespread use, it is important to report possible associations with disease, in this case meningitis.
View Article and Find Full Text PDFBackground: The epidemiology of meningitis is unknown in inflammatory bowel disease (IBD) patients.
Goals: We aimed to determine the incidence of and risk factors for meningitis in IBD patients.
Study: We conducted a retrospective cohort and nested case-control study in the Quintiles IMS Legacy PharMetrics Adjudicated Claims Database from January 2001 to June 2016.
Community-acquired Bacterial Meningitis in Adults With Cerebrospinal Fluid Leakage.
Clin Infect Dis
May 2020
Department of Neurology, Amsterdam Neuroscience, Amsterdam University Medical Centers, University of Amsterdam, The Netherlands.
Background: Cerebrospinal fluid (CSF) leakage is a risk factor for developing bacterial meningitis.
Methods: We analyzed episodes of community-acquired bacterial meningitis associated with CSF leakage from a prospective nationwide cohort study.
Results: CSF leakage was identified in 65 episodes of 2022 episodes (3%) in 53 patients.
[The duration of antibiotic therapy in bacterial meningitis with pyogenic ventriculitis].
Rinsho Shinkeigaku
March 2019
Department of Neuro-regeneration, Fukushima Medical University.
A 68-year-old man visited our hospital emergency department with consciousness disturbance. He was diagnosed as bacterial meningitis with septic shock, and initial empirical antibacterial therapy was initiated immediately. Streptococcus pneumoniae.
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