Transcranial direct current stimulation (tDCS) non-invasively modulates brain function by inducing neuronal excitability. The conventional hot spot for inducing the highest current density in the hand motor area may not be the optimal site for effective stimulation. In this study, we investigated the influence of the center position of the anodal electrode on changes in motor cortical excitability. We considered three tDCS conditions in 16 healthy subjects: (i) real stimulation with the anodal electrode located at the conventional hand motor hot spot determined by motor evoked potentials (MEPs); (ii) real stimulation with the anodal electrode located at the point with the highest current density in the hand motor area as determined by electric current simulation; and (iii) sham stimulation. Motor cortical excitability as measured by MEP amplitude increased after both real stimulation conditions, but not after sham stimulation. Stimulation using the simulation-derived anodal electrode position, which was found to be posterior to the MEP hot spot for all subjects, induced higher motor cortical excitability. Individual positioning of the anodal electrode, based on the consideration of anatomical differences between subjects, appears to be important for maximizing the effects of tDCS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.neulet.2014.10.052 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Individuals with general anxiety disorder (GAD) have an impaired future-oriented processing and altered reward perception, which might involve the ventromedial prefrontal cortex (vmPFC) and dorsolateral prefrontal cortex (dlPFC). Twenty-nine adults with GAD performed the balloon analogue risk-taking task (BART) and delay discounting task (DDT) during five sessions of transcranial direct current stimulation (tDCS) with different stimulation conditions. The stimulation conditions were: anodal dlPFC (F3)/cathodal vmPFC (Fp2), anodal vmPFC (Fp2)/cathodal dlPFC (F3), anodal dlPFC (F3)/cathodal right shoulder, anodal vmPFC (Fp2)/cathodal left shoulder, and sham stimulation.
View Article and Find Full Text PDFTranscranial direct current stimulation improves time perception in children with ADHD.
Sci Rep
December 2024
Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.
Individuals with ADHD struggle with time perception. The ventromedial prefrontal cortex (vmPFC) and dorsolateral prefrontal cortex (dlPFC) are two distinct cortical areas that are involved in the psychopathology of ADHD, including time perception. In the present study, we aimed to explore if modulation of the excitability of these areas with non-invasive brain stimulation alters time perception in ADHD.
View Article and Find Full Text PDFTranscranial Direct Current Stimulation Over Bilateral Temporal Lobes Modulates Hippocampal-Occipital Functional Connectivity and Visual Short-Term Memory Precision.
Hippocampus
January 2025
Department of Psychology, University of California, Riverside, California, USA.
Although the medial temporal lobe (MTL) is traditionally considered a region dedicated to long-term memory, recent neuroimaging and intracranial recording evidence suggests that the MTL also contributes to certain aspects of visual short-term memory (VSTM), such as the quality or precision of retained VSTM content. This study aims to further investigate the MTL's role in VSTM precision through the application of transcranial direct current stimulation (tDCS) and functional magnetic resonance imaging (fMRI). Participants underwent 1.
View Article and Find Full Text PDFHigh-density theta oscillatory-modulated tDCS over the parietal cortex for targeted memory enhancement.
Clin Neurophysiol
December 2024
Human Neuroscience Group, Centre for Neuroscience and Neuromodulation, Institute for Medical Research, University of Belgrade, Serbia.
Objectives: Associative memory (AM) declines due to healthy aging as well as in various neurological conditions. Standard transcranial electrical stimulation (tES) protocols show inconclusive facilitatory effects on AM, often lacking function specificity and stimulation focality. We tested the effectiveness of high-density electrode montage delivering anodal theta oscillatory-modulated transcranial direct current stimulation (HD-Theta-otDCS) over the left posterior parietal cortex (PPC), aiming to target AM in a spatially focused and function-specific manner.
View Article and Find Full Text PDFA Literature Review on Optimal Stimulation Parameters of Transcranial Direct Current Stimulation for Motor Recovery After Stroke.
Brain Neurorehabil
November 2024
Department of Rehabilitation Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulatory technique with potential in stroke rehabilitation by modulating cortical excitability. However, the optimal parameters, including electrode placement, current intensity, stimulation duration, and electrode size, remain poorly understood, and the interactions among these factors contribute to mixed results in motor recovery post-stroke. This review explores the various stimulation parameters and their impact on enhancing corticospinal excitability (CSE) and motor function recovery.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!