Lipidomics in the study of lipid metabolism: Current perspectives in the omic sciences.

Gene

Institute of Health Sciences-ICS, Federal University of Bahia-UFBA, Department of Biofunção, Laboratory of Biochemistry, Biotechnology and Bioproducts-LBBB, Salvador, Bahia, Brazil. Electronic address:

Published: January 2015

The advances in systems biology and in the development of new technological tools in analysis, as well as in the omic sciences, among which, metabolomics, and more specifically, lipidomics, have made it possible to investigate the structural and functional complexity of lipids in biological systems. Liquid chromatography and mass spectrometry are the analytical approaches most used in lipid research. Biomedical research, with the development of specific markers for lipids, together with new software development, have both enabled the early diagnosis of several illnesses, besides the evaluation of drug activity and treatment efficacy.

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http://dx.doi.org/10.1016/j.gene.2014.10.039DOI Listing

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