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Outcomes of Radical Radiotherapy (RT) or Chemoradiotherapy (CRT) in Surgically Inoperable Advanced Oral Cavity Cancer: A Single Center Experience.
Head Neck
December 2024
Department of Radiation Oncology, Tata Medical Center, Kolkata, India.
Background: Patients with locally advanced, surgically unresectable oral squamous cell cancers (SU-OSCC) are often treated with palliative intent. There is limited information on the outcomes of radical intent treatment with radiotherapy (RT) or chemoradiotherapy (CRT).
Methods: We retrospectively examined patients with Stage III/IV previously untreated SU-OSCC treated definitively from 2011 to 2021 in a single institution with RT or CRT with or without neoadjuvant chemotherapy (NACT).
Prognostic and Predictive Biomarkers of Oligometastatic NSCLC: New Insights and Clinical Applications.
JTO Clin Res Rep
December 2024
Department of Pulmonary Diseases, GROW Research Institute for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
This review discusses the current data on predictive and prognostic biomarkers in oligometastatic NSCLC and discusses whether biomarkers identified in other stages and widespread metastatic disease can be extrapolated to the oligometastatic disease (OMD) setting. Research is underway to explore the prognostic and predictive value of biological attributes of tumor tissue, circulating cells, the tumor microenvironment, and imaging findings as biomarkers of oligometastatic NSCLC. Biomarkers that help define true OMD and predict outcomes are needed for patient selection for oligometastatic treatment, and to avoid futile treatments in patients that will not benefit from locoregional treatment.
View Article and Find Full Text PDFThe Mid- and Long-Term Consequences After Surgically Treated Lisfranc Injuries: A Case Series and Review of the Literature.
Cureus
November 2024
Departement of Orthopaedic Surgery and Traumatology, HFR Fribourg, University of Fribourg, Fribourg, CHE.
Background Long-term follow-up data are difficult to collect, especially in uncommon foot injuries. Therefore, it is rare to find publications that include patient-reported outcomes. Therefore, a case series and systematic review are provided to evaluate mid- and long-term outcomes.
View Article and Find Full Text PDFDefining an Undergraduate Radiation Oncology Microclerkship via the Delphi Method.
Pract Radiat Oncol
December 2024
Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, MA; Harvard Medical School, Boston, MA.
Purpose: Many medical students in the U.S. lack formal exposure to radiation oncology (RO).
View Article and Find Full Text PDFA systematic review on patient perceptions and clinician-reported outcomes when comparing digital and analog workflows for complete dentures.
J Prosthodont
December 2024
Schulich School of Medicine and Dentistry, Department of Dentistry, Western University, London, Canada.
Purpose: To compare digitally fabricated complete dentures to conventionally fabricated dentures using patient- and clinician-reported outcome measures.
Methods: This review was structured according to PRISMA guidelines with the protocol registered in the PROSPERO database (CRD42024526069). An electronic search of the databases with a defined search strategy was completed within PubMed/MEDLINE and Web of Science from January 2000 to March 2024.
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