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Baseline and outcome stereoacuity of children with anisometropic amblyopia undergoing dichoptic amblyopia treatment.
J AAPOS
January 2025
Pediatric Vision Laboratory, Retina Foundation of the Southwest, Dallas, Texas; Optometry & Vision Science, University of Waterloo, Waterloo, Ontario, Canada.
Background: One rationale for dichoptic amblyopia therapy is that it may promote recovery of binocular function. Yet data on binocular outcomes in anisometropic amblyopia following dichoptic therapy are sparse. We report factors associated with pre- and post-treatment binocular function in anisometropic amblyopia, and examine binocular function in children who recover normal visual acuity compared to those with residual amblyopia.
View Article and Find Full Text PDFDifferential impacts of strabismic and anisometropic amblyopia on the mesoscale functional organization of the human visual cortex.
J Neurosci
January 2025
Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
We employed high-resolution fMRI to distinguish the impacts of anisometropia and strabismus amblyopia on the evoked ocular dominance (OD) response. Sixteen amblyopic participants (8 females) plus 8 individuals with normal vision (1 female), participated in this study for whom, we measured the difference between the response to stimulation of the two eyes, across areas V1-V4.In controls, the evoked OD response formed the expected striped pattern within V1.
View Article and Find Full Text PDFFixation Stability Deficits in Anisometropic Amblyopia.
Invest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-Sen University, Guangzhou, China.
Purpose: The purpose of this study was to investigate the relationship between fixation stability deficits in anisometropic amblyopia and various visual functions, as well as the underlying retinal structure.
Methods: All 164 patients with anisometropic amblyopia were recruited in this cross-sectional study. The contrast sensitivity function (CSF) was measured using the qCSF method, whereas the MP-3 microperimeter was used to assess fixation stability and locate the preferred retinal locus.
Occlusion Outcomes in Unilateral Amblyopia Types: A Longitudinal and Interventional Study in Children from the Marrakech-Safi Region.
Br Ir Orthopt J
December 2024
Laboratory of Electronic Systems, Mechanical, and Energy Information Processing, MA.
Objective: To investigate if the type of unilateral amblyopia can impact the improvement of visual acuity in amblyopic eyes during a longitudinal interventional study involving standard occlusion therapy in children.
Methods: A longitudinal and interventional study of 91 children, aged 3-9 years (6.12 ± 1.
Analysis of retinal nerve fiber layer and macular thickness in amblyopic children treated with occlusion therapy.
Strabismus
December 2024
Department of Ophthalmology, Hamad Medical Corporation, Doha, India.
: To study and evaluate the change in retinal nerve fiber layer (RNFL) and macular thickness and its clinical correlation with visual outcome following amblyopia therapy. : In this prospective interventional study, children with moderate to severe amblyopia were given optical correction and part-time occlusion therapy. Visual assessment and optical coherence tomography (OCT) were performed at days 0 and 3, 6 months of follow-up.
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