The genetics of diabetic pregnancy.

Best Pract Res Clin Obstet Gynaecol

Albert Einstein College of Medicine, Bronx, NY, USA; Natera, Inc., San Carlos, CA, USA. Electronic address:

Published: January 2015

Advancements in molecular technology coupled with a greater awareness of the human genome and epigenome have broadened our understanding of the genetic contributions to the diabetic pregnancy. There are multiple genes and pathways that can result in a hyperglycemic environment for the fetus. Exposure to this environment in utero has an impact on the risk of adult-onset chronic diseases. How identification of an individual's genetic variants will impact clinical care and outcomes will continue to evolve as our understanding grows.

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http://dx.doi.org/10.1016/j.bpobgyn.2014.08.008DOI Listing

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