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Surgical management of dysphagia due to diffuse idiopathic skeletal hyperostosis: the role of barium swallow fluoroscopy-a case report.
J Spine Surg
December 2024
Spine Clinic, Elsan Jean Villar Private Hospital, Bordeaux, France.
Background: Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic condition that might lead to dysphagia because of massive osteophytes that may be present at multiple levels. Confirming the symptomatic level to guide surgical management and avoid extensive surgery is important, however, there is no globally accepted consensus on the topic.
Case Description: We report the case of a 51-year-old man, with no specific past medical history, who has been complaining of a 3-months pain in the left side of the tongue base with sensation of a lump in the throat and dysphagia.
In a visual inverted pendulum balancing task avoiding impending falls gets harder as we age.
Exp Brain Res
January 2025
Ashton Graybiel Spatial Orientation Laboratory, Brandeis University, MS 033, 415 South Street, Waltham, MA, 02453, USA.
Younger adults (YA) and older adults (OA) used a joystick to stabilize an unstable visual inverted pendulum (VIP) with a fundamental frequency (.27 Hz) of half that of bipedal human sway. Their task was to keep the VIP upright and to avoid ± 60° "fall" boundaries.
View Article and Find Full Text PDFA novel wearable device integrating ECG and PCG for cardiac health monitoring.
Microsyst Nanoeng
January 2025
Key Laboratory of Instrumentation Science and Dynamic Measurement Ministry of Education, North University of China, 030051, Taiyuan, China.
The alarming prevalence and mortality rates associated with cardiovascular diseases have emphasized the urgency for innovative detection solutions. Traditional methods, often costly, bulky, and prone to subjectivity, fall short of meeting the need for daily monitoring. Digital and portable wearable monitoring devices have emerged as a promising research frontier.
View Article and Find Full Text PDFInitial Decline in Glomerular Filtration Rate With Finerenone in HFmrEF/HFpEF: A Prespecified Analysis of FINEARTS-HF.
J Am Coll Cardiol
January 2025
British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom. Electronic address:
Background: An initial decline in estimated glomerular filtration rate (eGFR) often leads to reluctance to continue life-saving therapies in patients with heart failure (HF).
Objectives: The goal of this study was to describe the association between initial decline in eGFR and subsequent clinical outcomes in patients randomized to placebo or finerenone.
Methods: In this prespecified analysis of FINEARTS-HF (Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients with Heart Failure), we examined the association between initial decline in eGFR (≥15%) from randomization to 1 month and subsequent outcomes in patients assigned to finerenone or placebo.
Development of a Framework for the Hemodynamic Impact of Positive End-Expiratory Pressure in Normal and Heart Failure Conditions.
Am J Physiol Heart Circ Physiol
January 2025
NTTR-NCVC Bio Digital Twin Center, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Positive end-expiratory pressure (PEEP) improves respiratory conditions. However, the complex interaction between PEEP and hemodynamics in heart failure patients makes it challenging to determine appropriate PEEP settings. In this study, we developed a framework for the impact of PEEP on hemodynamics considering cardiac function, by integrating the impact of PEEP in the generalized circulatory equilibrium framework, and validated the framework by assessing its ability to accurately predict PEEP-induced hemodynamics.
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