Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Abstract This review discusses the highlights of the recently made discovery about the ability of hormones to eject 'solvated electrons' (eaq-) in water containing media. The resulting consequences for communication with other biological systems by the electron-transfer process, formation of metabolites, the possible initiation of cancer, hormone regeneration and the action of hormone-receptor systems are briefly discussed. The molecular structure of the hormones and the environment are hereby found to be the most important determining factors for the yield of ejected eaq-. Furthermore, the hormone transients, which result from emission of eaq-, are reviewed, as well as the formation of metabolites, which can be involved in various biological processes. The hormone-transients can also be regenerated by electron-transfer from a potent electron donor, at least partly, as long as they are in a 'status nascendi state'. The discussion of all these effects is supported by corresponding experimental data and experiments in vitro. This review presents a complete new conception of the action mechanisms of hormones.
Download full-text PDF |
Source |
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http://dx.doi.org/10.1515/hmbci-2012-0024 | DOI Listing |
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