Cephalomedullary interlocking nails that allow for trochanteric entry and minimally invasive fixation have revolutionized the contemporary management of subtrochanteric fractures with improved union rates and decreased incidence of fixation failure. The most successful alternative to intramedullary fixation remains the angled blade plate. Despite biomechanical superiority of contemporary intramedullary implants to previous intramedullary devices, the importance of achieving and maintaining satisfactory fracture reduction prior to and during hardware insertion cannot be overemphasized. In comminuted and more challenging fractures, additional techniques, such as limited open reduction with clamps and/or cables, can allow for canal restoration and more anatomic reductions prior to and/or during nail insertion.
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http://dx.doi.org/10.1016/j.ocl.2014.09.001 | DOI Listing |
Pharmaceutics
January 2025
Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
A comprehensive review of recent research on niosomes was conducted using a mixed methodology, including searches in databases such as Scopus, PubMed, and Web of Science (WoS). Articles were selected based on relevance. The current review examines the historical development of niosomes focusing on the methods of preparations and the contemporary strategies and prospective advancements within the realm of drug delivery systems, highlighting innovative approaches across transdermal, oral, and cellular delivery.
View Article and Find Full Text PDFLife (Basel)
December 2024
Department of Zoology, Lahore College for Women University, Lahore 44444, Pakistan.
Hepatocyte carcinoma (HCC) is a globally prevalent neoplasm with profound effects on morbidity and mortality rates. This review summarizes the complex interactions between coagulation abnormalities and the pathophysiological mechanisms underlying HCC. Essential coagulation biomarkers, such as P-selectin, thrombomodulin, d-dimer, prothrombin, and von Willebrand factor, are reviewed for their diagnostic, prognostic, and therapeutic significance.
View Article and Find Full Text PDFAnn Vasc Surg
January 2025
Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, FL, USA.
The management of type B aortic dissection is one of the most challenging and debated topics in contemporary cardiovascular surgery practice. Patients with acute or chronic dissection-related complications, face high morbidity and mortality if not treated promptly. For most patients requiring intervention, thoracic endovascular aortic repair (TEVAR) is considered the gold standard.
View Article and Find Full Text PDFMusculoskelet Sci Pract
January 2025
University of Technology Sydney, Graduate School of Health, Australia.
Introduction: Gluteal tendinopathy is a prevalent and impactful condition. For many decades clinical practice has been guided by 'myths' that developed around clinical beliefs. It's time to examine these myths and engage with the substantial evidence base.
View Article and Find Full Text PDFPatient Educ Couns
January 2025
Department of Education Studies, University of Bologna, Via Filippo Re 6, Bologna, 40126, Italy. Electronic address:
Objective: Electronic health records (EHRs) have increasingly become integral to contemporary medical consultations, including pediatric care. This study aims at exploring the interactional use of the EHR during naturally occurring pediatric well-child visits, focusing specifically on how pediatricians and parents manage knowledge concerning infants' growth inscribed in the EHR.
Methods: Conversation analysis is used to analyze 23 video-recorded Italian well-child visits involving two pediatricians and twenty-two families with children aged 0-18 months.
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