It is shown in experiments on the rats subjected to gamma-radiation at various doses that preventive introduction of exogenous melatonin reduces the quantity ofchromosomal aberrations in cells ofbone marrow and decreases the expression of oxidative stress. After introduction of melatonin, the activity of leucocytes in peripheral blood and proliferation activity of splenocytes increase, which can play a role in the mechanisms for the genoprotective effect of the studied medication.
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