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Severe hypokalemia due to combination use of dexamethasone and calcium gluconate for diabetics with infection: a case report. | LitMetric

AI Article Synopsis

  • * A significant risk associated with this treatment is severe hypokalemia, which the patient developed and which caused symptoms like quadriplegia.
  • * The report highlights the biochemical confirmation of severe hypokalemia before the patient died from arrhythmia, and explores the underlying pathophysiological mechanisms as well as clinical guidelines for the safe use of these medications together.

Article Abstract

The combination use of dexamethasone and calcium gluconate can be applied to hypersensitivity. Severe hypokalemia is a usual complication of dexamethasone and calcium gluconate therapy, which occurs frequently with therapeutic use. Fatal cases, accidental and intentional, occur frequently in forensic practice. The current case report presented a 43-year-old man with diabetes mellitus with infection, to whom dexamethasone and calcium gluconate were administered in the private clinic. With the development of such clinical symptoms of severe hypokalemia as quadriplegia, he was confirmed to have severe hypokalemia through a biochemical test before dying of arrhythmia. And also it presented pathophysiologic mechanism underlying severe hypokalemia as well as suggestions for clinical practice regarding combination use of dexamethasone and calcium gluconate.

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