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http://dx.doi.org/10.1016/j.jcjo.2014.08.010DOI Listing

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Objective: Periorbital necrotizing soft tissue infection (NSTI) is a rare entity caused either by polymicrobial infection (type 1) or Streptococcus pyogenes and/or Staphylococcus species (type 2). A high level of clinical suspicion is necessary to make the diagnosis. We present 3 cases of NSTI illustrating our diagnostic and therapeutic approach.

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A 54-year-old female with myelodysplastic syndrome on chemotherapy presented with 10 days of periocular erythema and edema worsening on oral antibiotics. Computed Tomography scan showed periorbital soft tissue swelling without postseptal extension or abscess. Intravenous broad-spectrum antibiotics were administered.

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Purpose: Periorbital necrotizing fasciitis (NF) and sinusitis-related orbital cellulitis (OC) present with common clinical features, although the management algorithms for these ailments vary considerably. Previous investigations have failed to identify biomarkers that distinguish between these entities. This study was designed to explore the role of the derived neutrophil-to-lymphocyte and neutrophil-to-platelet ratios in discerning NF from OC.

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Article Synopsis
  • Necrotising fasciitis (NF) is a serious, fast-spreading infection known as "flesh-eating disease," primarily affecting soft tissues and leading to skin necrosis.
  • An elderly male developed periorbital NF after a minor head injury, showing symptoms like swelling and discharge, with a rare pathogen identified as the cause.
  • The treatment involved antibiotics, surgery, and skin grafting, resulting in significant recovery, highlighting the need for quick diagnosis and intervention to avoid severe outcomes.
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Utilization of hyperbaric oxygen therapy in oculoplastic surgery: A case series.

J Fr Ophtalmol

December 2024

Edward Harkness Eye Institute, Department of Ophthalmology, Columbia University Irving Medical Center, New York, NY, United States. Electronic address:

Objective: Hyperbaric oxygen therapy (HBOT) has emerged as a versatile tool in the management of an array of medical conditions, including tissue ischemia and delayed wound healing. Despite the incorporation of HBOT in other medical fields, HBOT is not routinely utilized in the field of ophthalmic plastic and reconstructive periorbital surgery.

Design: Case series.

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