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Two-Stage Mayo Clinic Class IIIb Celiac Axis Resection for Pancreatic Adenocarcinoma: Stepwise Management.
Ann Surg Oncol
December 2024
Division of Hepatobiliary and Pancreatic Surgery, NYU Langone Health, NYU Grossman School of Medicine, New York, NY, USA.
Background: The National Comprehensive Cancer Network guidelines consider pancreatic cancer with celiac axis (CA), proper hepatic artery (PHA), and superior mesenteric artery (SMA) involvement unresectable. Thus, technical reports and video illustrations of these operations are rare. We report the stepwise management of multivascular reconstruction for Mayo Clinic class IIIb CA resections at New York University Langone Health, a dedicated center of excellence in pancreatic surgery.
View Article and Find Full Text PDFAquaporins in Biliary Function: Pathophysiological Implications and Therapeutic Targeting.
Int J Mol Sci
November 2024
Department of Biosciences, Biotechnologies and Environment, University of Bari "Aldo Moro", 70125 Bari, Italy.
Aquaporins (AQPs) are transmembrane proteins permeable to water and a series of small solutes. AQPs play a key role in pathways of hepatobiliary secretion at the level of the liver, bile ducts, and gallbladder. AQP8 and -9 are pivotal in facilitating the osmotic water movement of hepatic bile, which is composed of 95% water.
View Article and Find Full Text PDFUnbiased and reproducible liver MRI-PDFF estimation using a scan protocol-informed deep learning method.
Eur Radiol
November 2024
Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile.
Objective: To estimate proton density fat fraction (PDFF) from chemical shift encoded (CSE) MR images using a deep learning (DL)-based method that is precise and robust to different MR scanners and acquisition echo times (TEs).
Methods: Variable echo times neural network (VET-Net) is a two-stage framework that first estimates nonlinear variables of the CSE-MR signal model, to posteriorly estimate water/fat signal components using the least-squares method. VET-Net incorporates a vector with TEs as an auxiliary input, therefore enabling PDFF calculation with any TE setting.
Evaluation of Minimum-to-Severe Global and Macrovesicular Steatosis in Human Liver Specimens: A Portable Ambient Light-Compatible Spectroscopic Probe.
J Biophotonics
December 2024
Department of Physics and Atmospheric Science, Dalhousie University, Halifax, Canada.
Background And Aims: Hepatic steatosis (HS), particularly macrovesicular steatosis (MaS), influences transplant outcomes. Accurate assessment of MaS is crucial for graft selection. While traditional assessment methods have limitations, non-invasive spectroscopic techniques like Raman and reflectance spectroscopy offer promise.
View Article and Find Full Text PDFPortal Vein Arterialization as a Lifesaving Strategy for Hepatic Artery Injury in Robotic Hepatectomy.
Ann Surg Oncol
January 2025
Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- Robotic vascular resection and reconstruction is complex, and portal vein arterialization (PVA) is an effective alternative when the hepatic artery can't be repaired, enhancing liver oxygen supply and promoting regeneration.
- A case study describes a 52-year-old man with cholangiocarcinoma who underwent robotic left-liver-first surgery, but sustained an artery injury, leading to the use of PVA for successful artery-portal vein anastomosis.
- The surgery lasted 490 minutes with a blood loss of about 300 mL, and although there was a bile leak post-surgery, the patient recovered without experiencing liver failure.
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